The use of antisense oligonucleotides (ASOs) was first identified, over twenty years
ago, as a method to arrest gene expression levels both in vitro and in vivo where
single-stranded DNA or RNA, in antisense configuration, can target a specific sense
mRNA. The strategies in the design and chemistry of antisense compounds have become
an effective tool in molecular biology basic research, genomics, proteomics, target
screening/validation and drug discovery.
No set up fee
Deprotected, desalted, lyophilized
Purification by PAGE or RP-HPLC upon request
QC analysis by MALDI-TOF Mass spec, HPLC or PAGE
Fast delivery with high throughput capacity
Product Pricing
|
Base
|
100 nmol
|
250 nmol
|
1 umol
|
5 umol
|
10 umol
|
|
Chimeric DNA base
|
0.85/base
|
$1/base
|
$2/base
|
$10/base
|
$18./base
|
|
Phosphorothioate Bond
|
$5.00/bond
|
$5.00/bond
|
$2/base
|
$30/bond
|
$30/bond
|
|
2'-OMe
|
$8.50/base
|
$13.50/base
|
$20/base
|
$85/base
|
$160/base
|
|
Constrained Nucleotide
|
$35/base
|
$38/base
|
$50/base
|
$200/base
|
375/base
|
|
5-Methyl dC
|
$50
|
$60
|
$90
|
$90
|
$360
|
|
RNase HPLC
|
$195
|
$195
|
$260
|
$365
|
$360
|
|
Na+ salt exchange
|
$80
|
$80
|
$80
|
$225
|
$225
|
|
A minimum will applied for oligo <10 bases. Yields and base price may vary depending
on type of antisense synthesis..
Unmodified RNA Purifications Yields
|
Purifications
|
100 nmol
|
250 nmol
|
1 umol
|
5 umol
|
10 umol
|
|
PAGE
|
1 ODs
|
2 ODs
|
15 ODs
|
50 ODs
|
100 ODs
|
|
Phosphorothioate Bond
|
1 ODs
|
5 ODs
|
20 ODs
|
100 ODs
|
200 ODs
|
|
2'-OMe
|
1 ODs
|
5 ODs
|
20 ODs
|
100 ODs
|
200 ODs
|
|
Constrained Nucleotide
|
1 ODs
|
5 ODs
|
20 ODs
|
100 ODs
|
200 ODs
|
|
5-Methyl dC
|
1 ODs
|
2 ODs
|
10 ODs
|
50 ODs
|
100 ODs
|
|
RNase HPLC
|
0.5 OD
|
1 ODs
|
5 ODs
|
25 ODs
|
50 ODs
|
|
The most trusted name in Quality Custom Synthesis