Custom Constrained Nucleotide (Lock Nucleic Acid)

- Modifications

5' Modifications

3' Modifications

Phosphorothioates

Others

We are committed to long-term continuous improvement and developing the incorporation of modifications and minor bases. If a modification that you desire is not listed below, please contact us. It may be available as a product under development or we may be able to add it to our list of R&D projects. Your feedback will assist Bio-Synthesis in ensuring that the modifications which we offer best address our customers' needs.

Each modification is an additional charge to the synthesis.

3'Modifications
Guaranteed Yield (OD)	5-10	15-20	35-40
Synthesis Scales:	0.2 µmol	0.4 µmol	1.0 µmol
3'-Biotin	$140.00	$160.00	$200.00
3'-Inverted abasic	$50.00	$60.00	$75.00
3'-Inverted deoxythymidine	$50.00	$60.00	$75.00
3'-Puromycin	$50.00	$60.00	$75.00
3' Terminal dideoxy-cytidine	$75.00	$85.00	$110.00
3'-TAMRA	$190.00	$225.00	$275.00
3'-Fluorescein	$90.00	$100.00	$125.00
3' Terminal deoxy-guanosine	$75.00	$85.00	$110.00
3'-LC Biotin	$140.00	$160.00	$200.00
3'-LC LC Biotin	$140.00	$160.00	$200.00
3'-Cholesterol	$140.00	$160.00	$200.00
3'-Amino Modifier (6 atom)	$50.00	$60.00	$75.00
3'-DY547 (Cy3T alternate)	$290.00	$350.00	$425.00
3'-DY647 (Cy3T alternate)	$290.00	$350.00	$425.00

Phosphorothioate Modifications
Guaranteed Yield (OD)	5-10	15-20	35-40
Synthesis Scales:	0.2 µmol	0.4 µmol	1.0 µmol
Phosphorothioate	$25.00	$28.00	$30.00

Other Modifications
Guaranteed Yield (OD)	5-10	15-20	35-40
Synthesis Scales:	0.2 µmol	0.4 µmol	1.0 µmol
18-Atom spacer (Hexaethylene glycol)	$30.00	$40.00	$55.00
3-Carbon linker	$30.00	$40.00	$55.00
9-Atom spacer	$30.00	$40.00	$55.00

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Custom Constrained Nucleotide (Lock Nucleic Acid)

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