Detection of Posttranslational Modification
Posttranslational Modification (PTM) is a key component that contributes to the diversity of the biological activities and affecting a wide range of protein characterization or cellular functions. Antisera raised against these protein modifications has shown to be an useful tools in the study of cell signaling, protein structure, function, localization, activity, maturation, disease diagnostic, etc.
While protein phosphorylation and methylation is considered the most common posttranslational modification, more than 200 different covalently attached modifications targeting most proteinogenic amino acids are known today. Bio-Synthesis has been an expert in providing custom-made modification specific peptides as antigens for antiserum production. All antibodies against posttranslational modifications are double purified at Bio-Synthesis against the sequence and the modified peptide to ensure specificity.
Contact us about your project and we will reply with a quote along with detailed information regarding your custom Modification Specific Polyclonal Antibody Production!