Peptide cocktail co-immunization strategy is recommended for the first-time user to generate antibodies against a particular antigen. Since peptide antibodies do not always recognize the native protein, due in large part to the differences in tertiary structure between a synthetic peptide of 10-35 amino acid and a folded protein. Multiple-peptide co-immunization strategy is an approach to increase the probability that a peptide project will work for multiple applications and recognize the native protein. The peptide cocktail polyclonal antibody strategy uses multiple peptide antigens derived from the same native protein into one set of animals. This two for one approach is intended to enrich the diversity of antibodies that are produced and to short-circuit potential failure if a single antigen does not produce an immune response. While this strategy is not necessarily applicable in all situations, there are real benefits that can be derived from the multiple-peptide immunization strategy.