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Peptide Nucleic Acid PNA Conjugates Custom PNA Synthesis Custom PNA Chimera Custom PNA Synthesis
 
Synthesis of 

peptide nucleic acids (PNAs)

was introduced by Nielsen, Egholm, Berg, and Buchardt in 1991 as a new, completely artificial DNA/RNA analog by replacing the sugar phosphate backbone of natural nucleic acids with a synthetic peptide backbone. Unlike DNA or DNA analogs, these peptide-like DNA structures have the ability to form extremely stable complexes with complementary DNA oligomers and resistance to hydrolytic reactions and, thus, not expected to be degraded inside a living cell. The impressive property of a PNA is its ability to form extremely stable complexes with complementary DNA oligomers. This stability suggests that PNAs are superior reagents in antisense and antigen applications, and creates other uses for which sequence specific. but thermally stable complexes are required.

With over 25 years of experience in synthetic nucleic acid /peptide experience, BSI has developed the expertise to deliver a diverse and broad range of custom peptide nucleic acid synthesis services.

Service Overviews
PNA Synthesis
PNA Conjugations
PNA Chimeras
Dual Labeled PNA
PNA Technology
Antisense Technology
   

 

 

The most trusted name in Quality Custom Synthesis.