Bio-Synthesis of large numbers of extremely affordable custom peptides has
never been easier ...
Bio-Synthesis has developed high throughput
custom peptide synthesis to meet the growing demands for synthetic peptides
in the proteomics boom. We offer parallel synthesis of small quantities of peptide
libraries with the fastest and most efficient high throughput, delivering 96 different
peptides, unbound, in a 96-well format. Each plate is individually tested for accuracy
and can be used for epitope mapping, libraries, protein characterization and much
more. This technique provides researchers the ability to order large numbers of
peptides at extremely affordable prices and delivered in a short time.
A major reason for the demand of high throughput peptide synthesis has been the
realization that synthetic peptides have become invaluable tools in elucidating
important contiguous epitopes that are essential for functional and structural domains
in proteins. In particular, the systematic screening with a series of overlapping
fragments, called epitope mapping or substitution analogues, needs short peptides
in large numbers although, in general, micro molar quantities are sufficient. In
this regard, the value of using synthetic peptides as probes in biochemistry and
pharmacology is comparable to the value of oligonucleotides in molecular biology.
The systematic use of peptides, however, has been limited by the cost, time and
special expertise or equipment required to provide a significant number of peptides
for evaluation. Therefore, BSI over the past several years has developed synthesis
platforms that are capable of the simultaneous synthesis of many peptides with FLEXIBILITY,
SPEED, and HIGH THROUGHPUT at an economic price, resulting in a great value to our
customers.
Quantity: 0.5-2 mgs
Length: 8-20 aa average 75% pure
96 crude peptides per plate in 96-well format
Optimized chemistries
No cross contamination
QC: MALDI-TOF Mass Spectrometry on all peptides
Including: Electronic PDF files of QC data ( 2D bar code)
Delivery: 7-10 days
N-terminal biotinylation
N-terminal acetylation
Non-standard residue incorporation
C-terminal amidation
Disulfide bridge formation (cyclization)
Epitope mapping
Alanine walking
Single amino acid mutation screening
Protein-protein interaction studies
Kinase motif discovery
Protease motif discovery