Protein Carrier Conjugation
Bio-Synthesis offers conjugation of peptides to a variety of immunogenic carrier
proteins and gel for use as immunogen or for affinity purification. A variety of
immunogenic carrier proteins such as Keyhole Limpet Hemocyanin (KLH), Diphtheria
toxoid has been use in conjugation with several conjugation chemistries. We also
offer coupling of peptide to various types of gel to create an immunosorbent, for
positive or negative selection of macromolecular binding entries, such as antibodies.
Serum production packages also available with large selection of host animals, to
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To order,
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Service Features:
Carrier
Keyhole Limpet Hemocyanin (KLH), Bovine Serum Albumin (BSA), Rabbit Serum Albumin
(RSA), Ovalbumin, Thyroglobulin, or Human Gamma Globulin (HGG). Other proteins are
available upon request.
Cross-Links
MBS (and other bi-functional linkers), which couple through sulfhydryl groups, and
glutaraldehyde, which couples primarily through alpha, sigma & epsilon amino
groups
* Amino Acid Analysis of Conjugates available upon request
References:
[1] Lee, A.C., Powell, J.E., Tregear, G.W., Niall, H.D. and Stevens,
V.C. (1980) A method for preparing b-hCG COOH peptide-carrier conjugates of predictable
composition. Mol. Immunol. 17; 749-756.