Contact Us
800.227.0627

Amylin(20 - 29), Islet Amyloid Polypeptide, IAPP (20 - 29), cat

Amylin(20 - 29), Islet Amyloid Polypeptide, IAPP (20 - 29), cat
Sequence (1LC):
SNNFGAILSP
Sequence (3LC):
NH2 - Ser - Asn - Asn - Phe - Gly - Ala - Ile - Leu - Ser - Pro - COOH
Catalog :
13724-01
Unit:
1 mg
Price/Unit:
$599  (For other quantities please Contact Us or call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442)
Purity:
>95%
Format:
Each vial contains lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt
Description:
This is amino acids 20 to 29 fragment of the cat islet amyloid polypeptide (IAPP), or amylin 20 to 29. Only a small number of animal species is known to show amyloidogenesis. These include human and nonhuman primates, cats, and raccoons, with this segment being important for amyloid formation. IAPP, a putative polypeptide hormone, is a product of pancreatic beta-cells and the major constituent of the amyloid deposits seen mainly in islets of type 2 diabetic humans and diabetic cats. The NFGAIL sequence, amino acid residues 22 to 27, forms aggregates similar to those of the entire IAPP. IAPP has been increasingly studied as a simple model for factors governing amyloid fibril formation.
Storage:
Store the peptide at -20°C. Keep container tightly
Product Usage:
This product is for research use only. Not for use in diagnostic or therapeutic procedures.
M.W.:
1019.1 g/mol
Reference/Citations:
  1. Zanuy, D. et al. Biophys. J. 84, 1884 (2003);
  2. Westermark, P. et al. Proc. Natl. Acad. Sc. 87, 5036 (1990).