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Can I use MAP peptide's primary amines for conjugation with microplex beads

If MAPs are used are lysine primary amines available for conjugation to microplex beads?

Regarding MAP, the lysines from MAP core are not available for conjugation, because peptide chains are branched from the alpha and epsilon amine groups of the lysines. The only available groups will be the –COOH group of the MAP and the N-terminus of the 4 or 8 branches of the peptide. In this case, instead of carboxylated polystyrene Luminex beads, they will have to use a different beads with different functional groups.

 

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