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bimane Labeled Peptide Synthesis

Does Bio-Synthesis offer the synthesis of Bimane Labeled Peptides?

Yes, Biosynthesis Inc. can attach monobromobimame or dibromobimane to peptide cysteine side chains.  This compound has Abs/Em = 395/490 nm. This popular thiol-reative fuorescent reagent is often widely used to detect various thiol-containing compounds, including  glutathione, N - acetylcysteine, mercaptopurine, and peptides and proteins that possess thiol groups, to form highly fluorescent thioether units in cells. it is fluorogenic upon reacting with thiol-containining molecules. In protein research, mBBr is widely used for structural studies on disulfide linkages and thiol - containing residues

Monobromobimane

monobimane labeled oligo

Dibromobimane

dibimane labeled oligo


Contact us for bimane labeled peptide synthesis services