Enhanced Diagnostic Tools
Molecular weight determination of intact proteins and peptides by mass spectrometry requires sufficient sample amounts to obtain good data and relatively pure protein preparation.
MALDI mass spectrometry and works well for small and large proteins in a range of solvents. Alternatively, the analysis can be conducted using electrospray (ESI) mass spectrometry that can give very accurate Mw determinations but requires a very pure sample.
Samples for MALDI-TOF analysis need to meet certain requirements for obtaining good spectra. The more careful you prepare samples (including early steps of isolation and preparation) the more likely a successful analysis will be. Here are some guidelines of which kind of treatment is advantageous for mass spectrometric analysis.
Samples can be submitted in liquid or solid form.
We do not accept organometallic compounds and polymers.
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