New nucleic acid diagnostic tool with enhanced hybridization and quantification power.
Shivarov et al. published their work using BNA-NC probes allowed for the quantitative and sensitive detection of different mutant alleles. This rapid, easy and reliable diagnostic method is expected to allow the detection of myeloid malignancies. View Video
As far as biotin we actually use Biotin TEG, a 15 atom mixed polarity spacer arm based on a triethylene glycol. The spacer acts to minimize steric hindrance between the biotin moiety and the oligo, thereby providing streptavidin easy access to the biotin for capture and immobilization of the oligo. We highly recommend using this longer spacer instead of C6 which require NHS labeling, a post synthetic conjugation.
If you have a query regarding any of our products or services,
please don't hesitate to submit your question below. A member of our support team
will review and answer your question as quickly as possible.