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Custom DNA Synthesis--"FASTEST services in the industry

DNA Modifications
Custom Oligo Arrays

isoCytosine (iso-dC) and isoGuanosine (iso-dG)

The technology developed by EraGen consists of two additional bases (isoCytosine (iso-dC) and isoGuanosine (iso-dG) that form the third base pair. Click on specification page for details.

IsoCytosine (iso-dC) Qty. 5'-Mod Internal 3' -mod
200 nmol 15 OD $230 $230 NA
1.0 µmol  35 OD $230 $230 NA
IsoGuanosine (iso-dG) Qty. 5'-Mod Internal 3' -mod
200 nmol 15 OD $250 $250 NA
1.0 µmol  35 OD $250 $250 NA

Purification

Desalt or cartridge (RP1) purification is acceptable for most common phosphoramidite modifiers. However, additional purification is strongly recommended for modifiers that require NHS-ester chemistry to conjugate a dye through an amine linker such as Molecular Probes dyes.

Minimum Guarantee Purified Yield

Due to the chemistry of many modifications, yield will be approximately 40 - 60 % less than a standard oligo. Please see our yield chart for details.

Quality Controls

Every oligo synthesized is strictly controlled for quality by using either MALDI-TOF mass spectrometry or polyacrylamide gel electrophoresis (PAGE) analysis. Final yields are determined using UV absorbance at OD260 In addition, we perform QC methods tailored to specific modifications, such as OD ratio measurement where appropriate.

For additional information, please Contact us.

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