Antigenic Peptide Antigen Design Assistance Polyclonal Antibody Production


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Antigenic Peptide

For over 20 years, Biosynthesis has provided custom antibody production services worldwide, including researcher at university, biotechnology and pharmaceutical institutions. We offer comprehensive services for polyclonal antibody production with large selection for host animals. Each of our facilities is operated under USDA license and hold an NIH Animal Welfare Assurance from the Office of Laboratory Animal Welfare.

	Antigen Design Assistance
	To maximize the probability that antibodies against a synthesized peptide will recognize the native protein in the target assay, antigen design is a key consideration when choosing a peptide sequence.

	Protein Structure
	If the 3D structure of the protein is known, this can of course greatly assist in choosing exposed epitopes. But in most cases, this information is unknown and so sequences must be chosen based on predictive algorithms.

	Hydrophobicity
	To counter the risk of selecting an epitope that is buried within the protein, Pacific Immunology utilizes a proprietary combination of software algorithms that help determine hydrophilic regions that are most likely to be immunogenic and exposed on the native protein.