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| Biosynthesis provides Custom PNA Synthesis Overview Synthesis of peptide nucleic acids (PNA's) waholm, Berg, and Buchardt in 1991, a new, completely artificial DNA/RNA analog by replacing sugar phosphate backbons introduce by Nielsen, Ege of natural ncueic acid with syntheic peptide backbone. From simple PNA synthesis, PNA-bioconjugates to Oligo chimera. You can design. We can help! |
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PNA Chimeras |
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Synthetic molecules that can bind with high sequence specificity to a chosen target in a gene sequence are of major interest in medicinal and biotechnological contexts. They show promise for the development of gene therapeutic agents, diagnostic devices for genetic analysis, and as molecular tools for nucleic acid manipulations. |
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Peptide Nucleic Acid Bioconjugates |
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The PNA molecules can be chemically linked to a variety of other chemical groups, as we detail below. These bioconjugates can be used in a variety of applications including but not limited to, Control of Gene Expression, Antisense Therapy, Cellular Uptake/Delivery, Drug/Effectors Delivery and many others. |
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PNA to Small Molecule Conjugates |
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Compounds such us inositol, ricin, sterols, opiods etc, and in general any structure of interest can be conjugated. |
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