 |
| For over 20 years, BioSynthesis has provided custom antibody production services worldwide, including researcher at university, biotechnology and pharmaceutical institutions. We offer comprenhensive services for polyclonal antibody production with large selection fo host animals. Each of our facilities is operated under USDA license and hold an NIH Animal Welfare Assurance from the Office of Laboratory Animal Welfare. |
|
|
|
| |
 |
|
Peptide Nucleic |
|
| |
Peptide Nucleic acid (PNA) is a nucleic acid analogy in which the sugar Phosphate backbone of natural nucleic acid has been replaced by a synthetic peptide backbone usually formed from N-(2-amino-ethyl)-glycine units, resulting in an achiral and uncharged mimic.
|
|
|
|
|
| |
 |
|
Hydrolytic |
|
| |
It is chemically stable and resistant to hydrolytic (enzymatic) Cleavage and thus not expected to be degraded inside a living cell. PNA is capable of sequence-specific recognition of DNA and RNA obeying the Watson-Crick hydrogen bonding scheme, and the hybrid complexes exhibit extraordinary thermal stability and unique ionic strength effects. It may also recognize duplex homopurine sequences of DNA to which it binds by strand invasion, forming a stable PNA-DNA–PNA triplex with a looped-out DNA strand. |
|
|
|
|
| |
|
| |
|
|
