Asrgene family is present in Spermatophyta. Its members are generally activated under water stress. We present evidence that In vitro , electrophoretic assays show a homo-dimeric structure for ASR1 and highlight strong non-covalent interactions tomato ASR1, one of the proteins of the family, accumulates in seed during late stages of embryogenesis, a physiological process characterized by water loss.between monomers prone to self-assemble. Direct visualization of single molecules by atomic force microscopy (AFM) confirms that ASR1 forms homodimers and that uncovers both monomers and dimers bind double stranded DNA. The