Enhanced Diagnostic Tools
Bio-Synthesis offers several unnatural bases or functional group oligonucleotide modifications for use in chemical ligation applications. These modifications include: 5'-iodothymidine (5'-iodo group), 3'-thiophosphate, and various modifications for click ligation.
Modifications use for chemical ligation can be incorporated at any position within an oligonucleotide at time of synthesis or post-synthetically. Dual HPLC purification is highly recommended for post-synthetic conjugation.
Contact us for Oligonucleotide Modification for Chemical Ligation.
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Quality Control: Analytical HPLC, Gel eletrophoresis, and MALDI-TOF Mass Spectrometry
Delivery times: 5-7 Working days
Shipping conditions: Room temperature
Storage conditions: -20 oC to -70 oC
Oligonucleotides are stable in solution at 4 oC for up to 2 weeks. Properly reconstituted material stored at -20 oC should be stable for at least 6 months. Dried DNA (when kept at -20 oC) in a nuclease-free environment should be stable for years.