Bio-Synthesis offers C12 Spacer oligonucleotide modification at various scales. 12-carbon atom spacer C12 is used to introduce a long spacer arm into an oligonucleotide. Spacer C12 can be incorporated in multiple additions to create exttremely long spacers. They can be placed between oligonucleotide, even though this spacer modification are often shown on the 5' terminal end of the oligonucleotide. Spacer C12 oligonucleotide modifications are often used for solid-phase immobilization of DNA probes or aptamers for microarray applications1,2, but can be used for any oligonucleotide-based application requiring a long spacer arm. Contact Bio-Synthesis for C12 Spacer Oligonucleotide Modification Service.
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-20 °C to -70 °C. Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.
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1. Reese, M.O., van Dam, R.M., Scherer, A., Quake, S.R. Microfabricated Fountain Pens for High-Density DNA Arrays. Genome Res. (2003), 13: 2348-2352. 2. Lao, Y-H., Peck, K., Chen, L-C. Enhancement of Aptamer Microarray Sensitivity through Spacer Optimization and Avidity Effect. Anal. Chem. (2006), 81: 1747-1754.