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Acrydite can be place placed at the 5' end of an oligonucleotide. The acrylamide group of acrydite modified oligo is covalently react with thiol-modified surface or can be incorporated into polyacrylamide gels during polymerization via a thioether bond. The immobilization leaves the oligonucleotides available for hybridization. The Acrydite modification is insensitive to heat and other denaturing agents.  Acrydite-modified oligos are stable in aqueous solutions over a wide range of temperature and pH. Contact Bio-Synthesis for more information about Acrydite Modified Oligonucleotide Synthesis Services.

Product Information

 

Product Name:

Acrydite Oligonucleotide Modification

Category:

Attachement Chemistry

Modification Code:

[5Acryd]

Structure:

Bio-Synthesis Inc. Oligo Structure

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.