Enhanced Diagnostic Tools
Bio-Synthesis offers photoswitchable oligo dye labeling. This photoswitchable marker belongs to the photosensitive spiroamide compounds which, upon photoswitching with UV illumination, form transiently fluorescent species. In the dark, the colored and fluorescent form of dye labeled oligo returns to the nonfluorescent state via thermal relaxation. Contact Bio-Synthesis for photoswitchable oligo dye labeling.
Bio-Synthesis photoswitchable labels can be incorporate at any position of an oligonucleotide via post synthetic conjugation, dual HPLC purification is required. Every oligo synthesized is strictly controlled for quality by using either MALDI-TOF mass spectrometry or polyacrylamide gel electrophoresis (PAGE) analysis. Final yields are determined using UV absorbance at OD260 In addition, we perform QC methods tailored to specific modifications, such as OD ratio measurement where appropriate.
Quality Control: Analytical HPLC, Gel eletrophoresis, and MALDI-TOF Mass Spectrometry
Delivery times: 5-7 Working days
Shipping conditions: Room temperature
Storage conditions: -20 oC to -70 oC
Oligonucleotides are stable in solution at 4 oC for up to 2 weeks. Properly reconstituted material stored at -20 oC should be stable for at least 6 months. Dried DNA (when kept at -20 oC) in a nuclease-free environment should be stable for years.