Because of the easiness to obtain antibodies capable of specifically recognizing different compounds, they are some of the best-known tools in biological research. The development in 1975 of the hybridoma technique by Milstein and Köhler allowed the production of monoclonal antibodies, advancement that in combination with other recombinant DNA technologies facilitated the development of the current therapeutic antibodies. That all antibodies are not created equal had been well established, a situation that provides more versatility to these research tools.
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