Advances in peptides and nucleic acids synthesis are promoting the development of bioconjugates, where these molecules are either cross-linked to each other or to other compounds to yield products with distinct properties. There are many applications in biomedicine where linking two active molecules can lead to up- or down-regulation of gene expression. These bioconjugates are not limited to peptide-nucleic acid derivatives, but either of these two moieties can be substituted by another compound such as a polysaccharide, lipid, synthetic polymer or small molecules. Depending on the bioconjugates’ nature they can have applications in qualitative/quantitative assays, targeting of specific cells for diagnostic and/or therapeutic purposes, transfer of compounds across cell membranes, modulation of certain biological activities and other uses. Learn more, click on pdf link below
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