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Enjoy a complete package of precision and convenience:
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Biosyn Detect mycoplasma contamination
Biosyn Detect viral contamination
Biosyn Detect known mutations and analyse candidate genes
Biosyn Detect intra- and inter-species contamination
Biosyn Enjoy multiple-platform technology in accredited facilities
Biosyn Consult with expert scientific staff free of charge
Biosyn Receive rapid and reliable results in two days
Biosyn Pay as little as $95/sample
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The availability of well-characterized, viable human tissues and cell lines accompanied by pertinent donor data is a prerequisite for a great deal of current biomedical and transplantation research. Unfortunately, the misidentification and cross-contamination of human tissue cell lines occurs frequently. It is estimated that over 20% of all established cell lines are misclassified by cell type or species of origin, and over 33% of all cell lines suffer inter- or intra-species cross-contamination (1-3). To aid clients in need of cell line identity validation, Bio-Synthesis (BSI) offers fast and reliable human cell line authentication services performed at accredited DNA testing facilities by scientists with experience in STR DNA profiling, SNP genotyping, high-resolution Luminex HLA DNA typing, tissue microarray analysis and bioinformatic data analyses. Our commitment to total quality management assures that our scientists employ efficient methods to confirming species' identity and detect cross-contamination, authenticating our client's cell lines in full compliance with NIH recommendations and scholarly journal guidelines.
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Cell Line Validation
Reference:
1. Drexler, H.G., Dirks, W.G. and MacLeod, R.A.F. (1999) Leukemia 13, 1601–7.
2. Drexler, H. G. et al. (2001) Blood 98, 3495–6.
3. Cabrera, C.M. et al. (2006) Cytotechnology 51, 45–50.
4. Chatterjee, R. (2007) Science 315, 928–31.
5. MacLeod, R.A.F. et al. (1999) Int. J. Cancer 83, 555–63.
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