Endotoxin Detection and Removal
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Endotoxin Highlight

Lipopolysaccharides (LPS), commonly known as endotoxins, are found in Gram-negative bacteria outer membrane. Much evidence has shown the ability of LPS in eliciting immune response in humans and animals including shock, coagulation, fever and inflammation. At high concentration, LPS evoke a massive circulation of macrophages and cause major clinical issue in septic shock treatment in human. Despite the complication that LPS can cause in human, LPS also post a major concern in animal research due to the ability of LPS in inducing immune response. During animal immunization, an antigen is introduced for specific antibody production against the antigen. However, the immune response is manifested with the presence of LPS and it often lead to the antibody production against LPS instead of the antigen introduced. Gram-negative bacteria such as E-coli gain much attention in bioengineering and microbiology research. E-coli are best known as the versatile host for protein expression, recombinant protein production and being a vector. Though, there are many benefits for using E-coli in research, the LPS that are in conjunction could affect the research accuracy and specificity. For that reason, LPS removal is crucial for all kind of animal research especially when it is related to gram-negative bacteria.

Bio-Synthesis provides rapid endotoxin detection that is approved. Despite the endotoxin detection service, we also offer customized endotoxin removal service for our customers. Our methods offer up to a 90% efficiency of endotoxin removal and with up to 80% protein recovery.

Hot Products
  • Custom Peptide Synthesis
  • Custom Oligo Synthesis
  • Custom Antibody Services
  • Protein Expression, Production and Purification
  • Organic Synthesis
  • Detection and Analysis
  • Bioconjugation
  • Catalog Products
20% Off

Offer is valid until the end of October 2012 Promo ID: ET06012012

Tell us about your project and we will reply with a quote along with detailed information regarding your custom production! Enter a known colleague of yours that readily uses endotoxin ananlysis and removal services and receive a discount of 5% off your next order through our Colleagues and Friends Referral Program !
Contact us now to get your project started!
Service across Genomic, Proteomic, Cell Biology
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