Bioconjugation Selection by Molecules

Biopolymers can be cross linked with one another to form a hybrid conjugate with two complementary functions. Whether the conjugate is a drug toxin for therapuetic delivery; chelating agent for radioimmunoconjugates; or adjuvants to increase immuno response. BSI can develop and perform them at GMP compliant manufacturing scales for clinical applications.

Biomolecule conjugates applications include but not limit to:

Conjugate

• Oligonucleotide-antibody conjugates
• Conjugation of Fluorephore (fluorescent dye, biotin/avidin)
• Oligonucleotide-carrier protein conjugates
• Peptide-carrier protein conjugates
• Carbohydrate-carrier protein conjugates
• Antibody-beads conjugates
• Antibody-drug conjugates (ADC)
• Polymer-drug-target ligand conjugation (RGD, EPR, DOTA)
• Oligonucleotide-beads conjugates
• siRNA-antibody conjugates with cleavable linker
• siRNA-cationic peptide conjugates
• Phycoerythrin-antibody conjugates
• Drug-protein conjugates
• Drug-KLH conjugates

Application

• Immuno PCR
• Molecule biology tools
• Production of anti-oligonucleotide antibodies
• Production of anti-peptide antibodies
• Production of anti-carbohydrate antibodies
• Diagnostic assays
• Targeted drug delivery
• Targeted Imaging
• Diagnostic assays
• siRNA delivery, gene knockdown experiments
• siRNA delivery, gene knockdown experiments
• Immuno detection
• Drug delivery
• Production of anti-drug Antibodies