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Specialty Peptide Synthesis
Specialty Peptide Synthesis

To provide you with quality peptide product for the results you can trust...

Custom Fluorescent Labeled Peptides

Bio-Synthesis offers a wide variety of fluorescent labeling services, which includes expert technical advice on the selection of correct fluorescent labels for your applications. In addition to our usual quality control data sheet, we also include excitation and emission spectra for each product. While radio labeled peptides require special handling procedures and are expensive, our extensive range of fluorescent labeled peptides can be readily introduced during chain assembly or post-synthetically in a cost effective manner. We have the capability to construct any viable fluorescent peptide at your request.

Stable isotope labeling is also available!

For additional information, please contact us or send an email to info@biosyn.com

Fluorescent Labeled Peptides

Amine Reactive Labeling from Bio-Synthesis provides a wide variety of fluorescent labeled peptides. The vast majority of labels are designed for amino acid labeling. Therefore, peptides can be labeled with an N-terminal free amine, internal sequence via amino acid side chain such as Lysine or Dap, or at the C-terminus of the peptide through the side chain of a lysine residue. Use the wavelength spectrum below to locate the label requirements for your research.

Spectrum

Fluorescent Resonance Energy Transfer (FRET) has been widely used in various biological applications. Peptide probes incorporating fluorescent donor/non-fluorescent acceptor combinations have been developed primarily for various detection of proteolysis and nucleic acid hybridization1,2 , receptor/ligand interactions3, distribution and transport of lipids4,5, membrane potential sensing6,7,8, cyclic AMP detection 9-14. BSI has a range of fluorescent labels suitable for use in FRET peptides.

To explore our FRET label peptides, click here!

Red Labels

  • 5-carboxytetramethylrhodamine [5TMR]
  • 5.6-carboxytetramethylrhodamine [5(6)TMR]
  • 6-carboxytetramethylrhodamine [6TMR]
  • Lissamine Rhodamine B [LRhodB]

Green Labels

  • 5-carboxyfluoresceine [5FAM]
  • 5,6-carboxyfluoresceine [5(6)FAM]
  • 6-carboxyfluoresceine [6-FAM]
  • Methoxy coumarin acetic acid

Other Fluorescence Labeled Peptide probes also available such as

  • FITC/5-FAM (N-Terminal, Y/N Ahx)
  • MCA (N-Terminal)
  • HYNIC (N-Terminal)
  • DTPA (N-Terminal)
  • Texas Red
  • Bodipy
  • Aminocoumarin
  • and many others...

If you are interested in using fluorescence peptide but not list in our page, please Contact us for a quote.

All custom labeled peptides includes:

  • HPLC Analysis
  • MALDI-TOP Mass Spectrometry
  • Certificate of Analyses
  • Optional services: Amino acid Analysis and Sequencing

Also available for Stable Heavy Isotopes, Unusual Amino Acids