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Newsletters – Biosynthesis
Home
Newsletters
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Bio-Synthesis Newsletter - November 2020
Micro RNAs (miRNAs) can modulate pain thresholds in dorsal root ganglion neurons. Chronic pain involves nerve damage causing neuropathic pain...
More
Bio-Synthesis Newsletter - October 2020
Currently, antivenom treatment is the only option to treat humans when bitten by toxic snakes, scorpions, spiders, ticks, or jellyfish..
More
Bio-Synthesis Newsletter - September 2020
Gene therapy involves replacement of defective genes by delivery of the correct genetic material to establish normal functions...
More
Bio-Synthesis Newsletter - August 2020
Recently three research groups reported that the CRISPR-Cas9 causes deletions in the genome when used to induce double-strand breaks in human pluripotent stem cells (hPSCs)...
More
Bio-Synthesis Newsletter - July 2020
Two new methods now enable high-resolution profiling of spliceosome transcripts. The “spliceosome” refers to a series of protein-RNA complexes that gain and lose proteins as pre-mRNA....
More
Bio-Synthesis Newsletter - June 2020
Recently a research team has analyzed 3,800-year-old Yersinia pestis genomes. The bacteria Yersinia pestis is considered as the cause of the plague. Humans can also get the plague, after being bitten...
More
Bio-Synthesis Newsletter - May 2020
Cromwell et al. in 2020 reported that the incorporation of bridged nucleic acids, BNAs, at specific positions within CRISPR-RNAs (crRNAs) significantly improves Cas9 DNA cleavage specificity in vitro and cells...
More
Bio-Synthesis Newsletter - April 2020
Increasing levels of oxidized nucleosides in human cerebrospinal fluids have been reported in Alzheimer patients. New research now suggests that the oxidation product...
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Bio-Synthesis Newsletter - March 2020
Recently a nanotechnology strategy was developed for the delivery of the CRISPR Cas gene editing system into cells using arginine nanoparticles to generate signal regulatory protein...
More
Bio-Synthesis Newsletter - February 2020
Recently a nanotechnology strategy was developed for the delivery of the CRISPR Cas gene editing system into cells using arginine nanoparticles to generate signal regulatory protein...
More
Bio-Synthesis Newsletter - January 2020
RNA can be specifically labeled with fluorophors or modified with nonstandard nucleotides as needed for a variety of applications in RNA research. A diverse collection of RNA...
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Bio-Synthesis Newsletter - December 2019
RNA can be specifically labeled with fluorophors or modified with nonstandard nucleotides as needed for a variety of applications in RNA research. A diverse collection of RNA...
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Bio-Synthesis Newsletter - November 2019
In drosophila, A’-form RNA helices drive microtubule-based mRNA transport. Bullock et al., in 2010, used NMR spectroscopy to describe the first tertiary structure...
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Bio-Synthesis Newsletter - October 2019
Guanine-rich DNA and RNA sequences can form secondary structures called G-quadruplex structures. Analytical tools that allow characterization...
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Bio-Synthesis Newsletter - September 2019
Conjugating drugs to fatty acids which cells can quickly metabolize for energy can trick cancer cells into taking up conjugated drug molecules...
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Bio-Synthesis Newsletter - July 2019
Lysophosphatidylcholine acyltransferase (LPCAT1), when dysregulated in cell tissue links common genetic alterations found in tumors...
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Bio-Synthesis Newsletter - June 2019
“Point-of-Care” tools can positively impact current health care. Recently a research group reported a new version of molecular beacons useful for ‘Point-of-Care” diagnostics....
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Bio-Synthesis Newsletter - May 2019
To avid infectious agents and pathogens, mammals and insects have evolved an immune system able to control and eliminate pathogens. In mammals, including humans, the innate ....
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Bio-Synthesis Newsletter - April 2019
A recent study sampled the microbe diversity that is able to survive in the International Space Station (ISS). The study revealed that humans take their microbes with them into space....
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Bio-Synthesis Newsletter - March 2019
Oligonucleotides modified with BNAs allow the design of splice-switching oligonucleotide (SSO) probes.Short, synthetic, oligonucleotides modified with...
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Bio-Synthesis Newsletter - February 2019
The year 1869 is considered as the year of the discovery of the Periodic Table of Chemical Elements. Therefore 2019 will be the 150th anniversary of the Periodic Table of Chemical Elements....
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Bio-Synthesis Newsletter - January 2019
Inosine present in the epitranscriptome and the ADAR1 protein establishes innate immune tolerance for endogenous host double-stranded RNA....
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Bio-Synthesis Newsletter - December 2018
BNA analogs are useful tools for gene silencing when using RNAi. Many chemically modified siRNAs have been investigated, among them were bridged ...
More
Bio-Synthesis Newsletter - November 2018
Micro RNAs (miRNAs) can modulate pain thresholds in dorsal root ganglion neurons. Chronic pain involves nerve damage causing neuropathic pain...
More
Bio-Synthesis Newsletter - October 2018
Currently, antivenom treatment is the only option to treat humans when bitten by toxic snakes, scorpions, spiders, ticks, or jellyfish. Bioactive small peptides..
More
Bio-Synthesis Newsletter - September 2018
Gene therapy involves replacement of defective genes by delivery of the correct..
More
Bio-Synthesis Newsletter - August 2018
Recently three research groups reported that the CRISPR-Cas9 causes deletions....
More
Bio-Synthesis Newsletter - July 2018
Two new methods now enable high-resolution profiling of spliceosome transcripts....
More
Bio-Synthesis Newsletter - June 2018
Recently a research team has analyzed 3,800-year-old Yersinia pestis genomes....
More
Bio-Synthesis Newsletter - May 2018
Cromwell et al. in 2018 reported that the incorporation of bridged nucleic...
More
Bio-Synthesis Newsletter - April 2018
Is 8-oxo-7,8-dihydroguanosine a biomarker for aging?
More
Bio-Synthesis Newsletter - February 2018
Recently a nanotechnology strategy was developed for the delivery of the CRISPR Cas gene editing...
More
Bio-Synthesis Newsletter - January 2018
Synthetic oligonucleotides conjugated to minor groove binding(MGB) compounds exhibit enhanced DNA...
More
Bio-Synthesis Newsletter - December 2017
RNA can be specifically labeled with fluorophors or modified with nonstandard nucleotides as...
More
Bio-Synthesis Newsletter - November 2017
In drosophila, A’-form RNA helices drive microtubule-based mRNA...
More
Bio-Synthesis Newsletter - October 2017
Large intergenic non-coding RNAs (lincRNAs) are now emerging as key...
More
Oligonucleotide Peptide Sale
Bio-synthesis is a biology contract manufacturer of high quality...
More
New Publication - Bridged Nucleic Acids
Bio-synthesis Inc. is pleased to announce a new publication...
More
Bio-Synthesis Newsletter - september 2017
TERRA RNA refers to long noncoding telomeric repeat-containing RNAs...
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Bio-Synthesis Newsletter - August 2017
Recently, a CRISPR-Cas9 based in-vivo genetic screening approach...
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Bio-Synthesis Newsletter - July 2017
Molecular Inversion Probes (MIPs) are single-stranded DNA molecules...
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Bio-Synthesis Newsletter - June 2017
Genome editing using the CRISPR-Cas9 nuclease system is a powerful...
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Bio-Synthesis Newsletter - May 2017
Recently researchers have shown that sulforaphane, a dietary molecule...
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Bio-Synthesis Newsletter - April 2017
Telomeres DNA is located at the ends of eukaryotic chromosomes where they protect them...
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Bio-Synthesis Newsletter - March 2017
Bio-Synthesis is your one-stop provider for custom made RNA, DNA, Oligonucleotides...
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Bio-Synthesis Newsletter - February 2017
Our BNA Clamping Kit allows for selective and ultra-sensitive detection of BRAF V600E...
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Bio-Synthesis Newsletter - January 2017
Yes, this appears to be the case. A recent study suggests that albuminuria, a condition where...
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Bio-Synthesis Newsletter - december 2016
WorldB AIDS DayB is observed on December 1, drawing attention to the status of the...
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Bio-Synthesis Newsletter - November 2016
Synthetic RNA is well suited for CRISPR-Cas based gene editing experiments. Genome editing...
More
Bio-Synthesis Newsletter - October 2016
Guanine-rich DNA and RNA sequences can form secondary structures called G-quadruplex...
More
Bio-Synthesis Newsletter - September 2016
Recent research suggests that muscle aging could be slowed down.Studying young ....
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Bio-Synthesis Newsletter - August 2016
Recently a short peptide, CAQK, that allows targeted delivery of imaging and therapeutic compounds....
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Bio-Synthesis Newsletter - July 2016
Plants now know how to evade man-made herbicides. In recent years, many weeds have become....
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Bio-Synthesis Newsletter - june-2016
Epidemiological and proteomics studies confirmed that eating cruciferous vegetables reduce the....
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Bio-Synthesis Newsletter - May-2016
Bio-Synthesis has developed a new BNA based clamping kit for the detection of the BRAF V600E mutation....
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Bio-Synthesis Newsletter - March-2016
Recently a new type of cell-penetrating molecules has been designed. Researchers at Stanford University designed....
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Bio-Synthesis Newsletter - Feb 2016
CRISPR based gene editing systems are now used around the world.Recent research indicates that optimized CRISPR-Cas...
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Enhance your Gene Target efficiency using Synthetic Long RNAs for CRISPR/Cas9
CRISPR (clustered regularly interspaced short palindromic repeat) loci and a diverse cassette of CRISPR-associated...
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Oligo Labeling for Non-Radioactive Hybridization Probes.
In spite of significant advances in the detection of fluorescent and luminescent labels, oligo-enzyme conjugates continue....
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Real-Time PCR Probes
Real-time PCR is one of the most powerful hybridization-baseddiagnostic assays in use today. Real-time PCR allows one to detect and measure the progress.
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Modified peptides? We Can Help.
At Bio-Synthesis we are ready to assist with ALL your custom peptide needs. With over 30 years of experience in peptide synthesis,...
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Peptides are Reported to Prevent Viral Attacks
Many people die each year as a result of viral infections caused by the flu and various colds. Although this is an urgent ...
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Do Chemopreventive Peptides Prevent Disease ?
Chemopreventive peptides are reported to be effective in preventing diseases such as cancer and diabetes. These...
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BSI Celebrates 30
th
Anniversary
Bio-Synthesis provides custom long RNA molecular controls generated from a DNA template containing a bacteriophage promoter...
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Nucleic Acids Anniversary Sale!
Bio-Synthesis offers many options for oligonucleotide synthesis ranging from standard to specialty long oligo synthesis, modifications in a variety...
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Analytical Services
Are you looking to get more information out of your sample? Let Bio-Synthesis' analytical services help paint you a clearer picture....
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Enjoy the Summer Savings
Custom Peptide Synthesis – Bio-Synthesis specializes in long, complex and hydrophobic peptides synthesized to your exact needs, including...
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Using BNA Oligos to Advance Your Research
Are you looking to increase the stability of your oligos? Do you want better hybridization? Bio-Synthesis has the solution - an exclusive...
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Ultra Long RNA as Molecular Controls
The ability to synthesizes target RNA such as mRNA is critical for certain molecular biology techniques and genomic studies. Whether...
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Quality Bioreagent Fast Delivery
Have you been frustrated with orders that are poor in quality and slow in delivery?...
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Triphosphates Oligo
Bio-Synthesis provides high quality 5' modified triphosphate DNA and RNA synthesis using a robust, ...
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Molecular mass analysis of antibodies
Mass analysis of recombinant proteins is a key characterization method used...
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Large Volume IgG
Need high recovery and large volume purified antibody in a hurry but short of funding? Bio-Synthesis...
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Costmetic Peptides
Peptides have a wide application in medicine including the dermatology field. It is not surprising that these....
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Neurodegenerative Diseases
β-Amyloid (1-28), (1-40), (1-42), (1-43) to (1-49), (1-55) and Related Peptides...
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Alzheimer-Research
Amyloid Precursor Protein (APP) is a transmembrane protein that is predominantly...
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Endotoxin Highlight
Lipopolysaccharides (LPS), commonly known as endotoxins, are found in Gram-negative bacteria...
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CPP Peptides
Cell penetrating peptide bioconjugation as transporting vehicle for large-cargo molecules ...
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Glycopeptides
Advanced glycation end products (AGEs) are a class of compounds formed from non-enzymatic....
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Protein Expression
There are many factors to consider when choosing the optimal system for protein expression...
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Antibodies
Finding the high quality and reliable antibody that works for your demanding immunoassay...
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Long RNA Synthesis
As the capabilities of RNA analysis expand, the need to obtain a standardized RNA fragment...
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Cell Validation
Cell line contamination has been plaguing researchers since the beginning of the discipline...
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Constrained Peptides
Biosynthesis, Inc. has launched a new peptide conformation screening tool called positional cyclization ...
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RNase free water
Highly purified water has become an important reagent in molecular biology. Experiments that involve the use of reverse-transcriptase ...
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Antibody Services
Are you looking for high-quality custom services for your protein characterization and detection? ...
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Human Cell Line
The availability of well-characterized, viable human tissues and cell lines accompanied by pertinent...
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Triphosphate
Both DNA and RNA 5’-triphosphates (TP’s) play an important role as substrates for several...
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Sample Preparation Kit
As the summer heats up, so do our discounts! For the rest of the summer...
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Peptide Libraries
For over 25 years Bio-Synthesis has been manufacturing custom libraries/arrays, reliably...
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Bioconjugation
Selective delivery of molecules to cells, including large proteins and drugs, can be achieved...
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Antibodies
When using antibodies in your research, you are often worried if they will work...
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final yield.
Indicated yields are valid for unmodified Oligos of > 20 nt.
Indicate your minimum required yield in the "Item Notes" box.
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