⌘ Services

Custom Synthesis CDMO for Nucleic Acids, Peptides & Bioconjugates

Advanced synthesis, modification, conjugation, analytical, and scale-up support for research, diagnostic, and therapeutic development programs.

ISO 9001:2015 / ISO 13485:2016 45+ Years of Expertise U.S.A. Facilities-Texas GLP-Aligned Fit-For-Purpose QC

One Scientific Partner for Custom Synthesis, Complex Chemistry & Development support

Bio-Synthesis brings nucleic acid synthesis, peptide manufacturing, bioconjugation, molecular biology, analytical testing, and scale-up support together within one scientific organization.

Custom DNA, RNA, siRNA, ASO, probes, primers, and specialty oligonucleotides with extensive modification, conjugation, purification, and scale-up capabilities.

Custom peptide synthesis from research through development, including difficult sequences, advanced modifications, purification, analytical characterization, and scalable manufacturing.

Project-specific conjugation of oligonucleotides, peptides, proteins, antibodies, lipids, fluorophores, targeting ligands, polymers, and small molecules.

Custom cloning, gene synthesis, mutagenesis, recombinant DNA workflows, sequencing support, assay development, and project-specific molecular biology services.

Ready-to-order specialty research reagents supporting molecular biology, peptide research, assays, diagnostics, and life-science workflows.

Process-driven development, analytical, quality, and manufacturing support for programs progressing from research toward larger-scale and therapeutic applications.

Complex Oligonucleotides &
Conjugates Are a Core Strength

When a project involves an unusual modification, difficult sequence, multiple conjugations, specialized linker chemistry, or demanding scale-up requirements, Bio-Synthesis can help evaluate manufacturability and develop a practical synthesis strategy.

Modified DNA & RNA

siRNA & ASO

Peptide–Oligo Conjugates

GalNAc & Targeting Ligands

Lipid & Cholesterol Conjugates

Fluorescent & Imaging Probes

Specialty Linkers

Advanced Oligo Architectures

Advance from Feasibility to Development-Ready Manufacturing

Support across the development path—from early custom synthesis and chemistry optimization through analytical characterization, process development, scale-up, and manufacturing readiness.

CDMO capabilities workflow from research and discovery to custom synthesis, chemistry development, and therapeutic development

45+

Years of Expertise

Supporting biotechnology, pharmaceutical, diagnostic, and life-science organizations since 1984.

100,000+

Successful Projects

Experience across custom synthesis, complex chemistry, analytical support, and development programs.

U.S.-Based

Manufacturing & Scientific Support

Integrated synthesis and development support from Lewisville, Texas.

Experience for Projects That Go Beyond Routine Synthesis

Integrated chemistry and scientific support for standard projects as well as difficult sequences, specialized modifications, advanced architectures, and custom conjugates.

Complex Chemistry

Advanced modifications, specialty molecules, and challenging synthesis programs.

Integrated Capabilities

Nucleic acids, peptides, bioconjugation, molecular biology, purification, and analytics.

Analytical Confidence

Fit-for-purpose analytical characterization and QC aligned with project requirements.

Scalable Support

Scientific and manufacturing support from research through process development and scale-up.

Partner with an Experienced Custom Synthesis CDMO

From a specialized research molecule to a complex development program, Bio-Synthesis brings synthesis chemistry, analytical capability, and manufacturing experience together.

Scientific Collaboration

Chemistry Development

Research-to-Therapeutic Support

Let’s Start the Conversation

Tell us about your project and our team will connect with you to explore how we can help.

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Researcher Notice: Website information and scientific guidance are provided as general information. Researchers remain responsible for experimental design and specifications submitted to Bio-Synthesis for production feasibility review.

Why Choose Bio-Synthesis

Trusted by biotech leaders worldwide for over 45 years of delivering high-quality, fast, and scalable synthetic biology solutions.