Key Features of Our Large Scale Peptide Production
- High control production process
- Dedicated staff and facilities
- Flexible tailor-made Solution
Peptide applications play an important role in biochemistry, molecular biology, immunology and medicine. In the human body, most if not all biological/physiological processes are regulated by various forms of molecular recognition. Most of these processes involve initiation or inhibition trough protein-protein interaction. As we know, peptides and proteins due to the vast number of conformational possibilities are ideal to carry out such complex control functions. Synthetic peptides have been widely used for the following purposes:
- structure-function studies of polypeptides
- as peptide hormones and hormone analogues
- in the preparation of cross-reacting antibodies
- in the design of novel enzyme
- and in drug discovery.
The last 40 years have seen an enormous growth in the methodologies available to obtain peptide and protein molecules. Through recombinant methods, most labs can now assemble genes, subclone them into expression vectors and obtain a wide range of endogenous proteins. Likewise the pioneering work of Bruce Merrifield, makes it possible to obtain large scale with multi-kilo amounts of a number of biologically active peptides.
Bio-Synthesis has been producing synthetic peptides for over 28 years. Our expertise in custom synthetic polypeptide manufacturing allows us to produce high-quality, large-scale, and GMP peptides. We have delivered more than 100,000 peptides to customers worldwide, including very hydrophobic polypeptides, peptides with multiple disulfide bonds, multi-phosph0rylated peptides and extremely long peptides. Our largest scale non-GMP ever delivered was 5 kilograms of peptides on a single order and has the capacity of 10,000 peptides per month. Our capacity of GMP peptide is 10 kilograms.
Contact us for more information on large scale peptide production.
Large-Scale Peptide Services
All peptides undergo stringent quality control. Peptide delivery consists of lyophilized peptides of the required sequence, purity, and quantity and associated QC reports.
Example of nonGMP CMO Peptide Release
||Up to 1 Kilogram
||Up to 100 AA
|Parameter Qualification & Report
|Routine Project Update
|Pilot scale peptide preparation
|Customer Request Analysis
|Analytical Method Development
|Customer-requested Package & Delivery
Custom Preparative Services
If Custom preparative services are list below, please contact us. We can always accommodate your needs.
- Custom Normalized Tubes
- Peptide Arraying
- Counter-ion exchange(TFA removal Services)
- Endotoxin Testing and Removal
- pH Adjustment
- Peptide for Control
- Scrambled version Peptide
- Custom aliquot
- Custom Label, boxing and packaging
Extensive Quality Analysis
If Custom Analysis Service not list below, please contact us. We can always accommodate your needs.
- Amino Acid Analysis
- Peptide Sequencing
- Endotoxin Testing
- Solubility Testing
- Chromatography (HPLC,TLC,GC,IC)
- Chromatography coupled to MS(LC-MS/ESI)
- Metallic Analysis(AAS,ICP,ICP-MS)
- Titration(Acid-Base Titration Karl Fischer Titration)
- Cleavage Test and more...