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2,4-Dinitrophenyl (DNP) Oligo Modification
2,4-Dinitrophenyl (DNP) Oligo Modification

2,4-dinitrophenyl (DNP)

Oligonucleotides labelled with DNP (2,4-dinitrophenyl) can be used in analytical tests based on anti-DNP antibodies. This DNP with triethylene glycol (TEG) spacer can be introduced anywhere in the sequence and on either terminus.

TEG-Dinitrophenol Desalted Qty. 5'-Mod Internal 3' -mod
250 nmol 15 OD $265 NA NA
1.0 µmol 35 OD $350 NA NA
Dinitrophenol Desalted Qty. 5'-Mod Internal po3' -mod
250 nmol 15 OD NA $280 NA
1.0 µmol 35 OD NA $380 NA


Desalt or cartridge (RP1) purification is acceptable for most common phosphoramidite modifiers. However, additional purification is strongly recommended for modifiers that require NHS-ester chemistry to conjugate a dye through an amine linker such as Molecular Probes dyes.

Minimum Guarantee Purified Yield

Due to the chemistry of many modifications, yield will be approximately 40 - 60 % less than a standard oligo.Please see our yield chart for details.

Quality Controls

Every oligo synthesized is strictly controlled for quality by using either MALDI-TOF mass spectrometry or polyacrylamide gel electrophoresis (PAGE) analysis. Final yields are determined using UV absorbance at OD260 In addition, we perform QC methods tailored to specific modifications, such as OD ratio measurement where appropriate.

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