Bio-Synthesis offers monobromobimane (mBBr, monobimane) fluorescent dye oligonucleotide labeling services. Monobimane is a heterocyclic compound that are fluorogentic upon reacting with thiol-containing molecules. In protein research, mBBr is widely used for structural studies on disulfide linkages and thiol - containing residues. 

Monobromobimane  can be incorporated at any position within an Oligonucleotide. Dual HPLC purification is used to remove failure sequences during first HPLC purification,  after labeling, the second HPLC is performed to remove unlabeled oligonucleotides and excessive dye in order to obtain a full length labeled oligonucleotide.

Contact us for Monobromobimane Labeled Oligonucleotide service.

Product Information


Product Name:

Monobromobimane Oligo Dye Labeling

Alternate Name:

mBBr, Monobimane, Bimane


Fluorescent dye Label, Bimane

Absorption λmax:


Emission (nm):



Bio-Synthesis Inc. Oligo Structure


dual HPLC required

Delivery Format:


Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.