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DNA Modifications
Custom Oligo Arrays

Rhodamine Dyes

Rhodamine derivatives are not sufficiently stable to survive conventional deprotection and these must be attached to amino-modified oligonucleotides using post-synthesis labeling techniques for 5' labeling.

This compound requires amino- or thiol- linker with a 6-Carbon spacer arm or by substituting any thymidine with 5-C6-Amino-2'-deoxythymidine for internal labeling, a double HPLC purification is required.

Contact your Account Representative for pricing on rhodamine dye labeled oligonucleotides. For additional information, please Contact us.

Price/labeling, purification and synthesis is an additional charge

Dyes Scales Label position
5'-Mod Internal 3' -mod
Rhodamine GreenTM-X NHS Ester 250 nmol $195 $220 $195
1.0 µmol $250 $300 $250
Rhodamine RedTM-X NHS Ester 250 nmol $195 $255 $195
1.0 µmol $295 $345 $295
TAMRATM 250 nmol $225 $315 $135
1.0 µmol $395 $345 $150
TAMRATM NHS Ester 250 nmol $125 $200 $135
1.0 µmol $195 $250 $195
ROXTM NHS Ester 250 nmol $170 $200 $160
1.0 µmol $225 $275 $225


Desalt or cartridge (RP1) purification is acceptable for most common phosphoramidite modifiers. However, additional purification is strongly recommended for modifiers that require NHS-ester chemistry to conjugate a dye through an amine linker such as Molecular Probes dyes.

Minimum Guarantee Purified Yield

Due to the chemistry of many modifications, yield will be approximately 40 - 60 % less than a standard oligo.

Please see our yield chart for details.

Quality Controls

Every oligo synthesized is strictly controlled for quality by using either MALDI-TOF mass spectrometry or polyacrylamide gel electrophoresis (PAGE) analysis. Final yields are determined using UV absorbance at OD260 In addition, we perform QC methods tailored to specific modifications, such as OD ratio measurement where appropriate.

For additional information, please Contact us.

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