Aptamers are short, single-stranded DNA or RNA (ssDNA or ssRNA) molecules that are generated through repeated selection using SELEX or an equivalent in-invivo procedure upon specific targets.These targets which are useful in therapeutics include proteins, peptides, carbohydrates, small molecules and toxins. Bio-Synthesis offers various nucleic acid aptamers that can be developed rapidly by in-vitro methods due to their inherent reproducibility and stability. A full array of bases, suars and inter-nucleotide modifications are available at Bio-Synthesis for custom oligonucleotide synthesis.

contact us for affinity ligand modified oligonucleotide synthesis services.

Our Advantages

  • Wide selection of modified RNA,DNA bases beyond 5-Mthyl C
  • Flexibility in oligo length and synthesis scales
  • Oligonucleotides are delivered as deprotected, desalted and/or purified
  • Quality checked by MALDI-TOF/LC-MS, analytical HPLC, PAGE
  • Specialize in producing newly-discovered and difficult -to-make modified bases
Product Modification Code 5 Prime Internal 3 Prime
L-DNA base [L-A],[L-C],[L-G], [L-T] Y Y Y
Locked Nucleic Acid [AL], [CL],[GL], [TL] Y Y Y
L-RNA Base [L-rA],[L-rC],[L-rG], [L-rU] Y Y Y
2 Fluoro base fA, fU, fG, fC Y Y Y
2’OMe mA, mC, mG, mU Y Y Y
2’MOE [eC], [eG], [eT], [eA] Y Y Y

Quality Control: Analytical HPLC, Gel eletrophoresis, and  MALDI-TOF Mass Spectrometry

Delivery times: 5-7 Working days

Packaging:    Dried

Shipping conditions: Room temperature

Storage conditions: -20 oC to -70 oC

Oligonucleotides are stable in solution at 4 oC for up to 2 weeks. Properly reconstituted material stored at -20 oC should be stable for at least 6 months. Dried DNA (when kept at -20 oC) in a nuclease-free environment should be stable for years.

Ordering & Contact Information

  • Please contact us for additional information or send an email to info@biosyn.com.
  • You may also request an online quote.
  • To contact us by phone, please Call 972-420-8505 (USA) 800-227-0627 (INTL.) or Fax 972.420.0442
  • Orders may be placed using a purchase order (PO) or by credit card through our secure online ordering system.
  • When using a credit card ( creditcard ) it will be billed under "Bio-Synthesis, Inc."