800.227.0627

Oligonucleotide Chemist II

Location: Lewisville, TX, USA

JOB Details

Perform the complex synthesis, purification, and comprehensive analysis of oligonucleotides, including DNA, RNA, and chemically modified oligos or peptides, employing advanced, high-throughput methodologies and cutting-edge technologies to achieve superior yields and exceptional purity; Execute and manage cleavage, deprotection, desalting, and purification protocols with high precision, ensuring complete purity and integrity of oligonucleotides through rigorous analytical testing and quality control measures; Oversee the packaging, documentation, and release of synthetic oligonucleotides and peptides, ensuring adherence to regulatory requirements and industry best practices while maintaining impeccable traceability and detailed process records; Perform routine and preventative maintenance on Mermade Synthesizer, Dr. Oligo Synthesizer, annealing Oligonucleotides optimizing equipment performance, identifying potential issues, and ensuring smooth operation to minimize downtime and maintain continuous production flow; Utilize advanced quantitative analysis skills to evaluate complex data sets, employing sophisticated data management tools like Excel and other platforms Microsoft Power Platform to perform detailed trend analysis using ChemDraw, SciFinder, reaxys, track synthesis progress, and drive process improvements; Work in close collaboration with multidisciplinary teams to drive project timelines, present technical findings, and contribute to strategic decision-making processes.

Download Form PDF