800.227.0627

Definition

Protein phosphorylation is a post-translational modification of proteins in which a serine, a threonine or a tyrosine residue is phosphorylated by a protein kinase with the addition of a covalently bound phosphate group. There are several protein phosphorylation related peptides that belongs to regulatory domain of kinases used for studying the physiological role of enzymes.

Discovery

In 1906, Phoebus A. Levene at the Rockefeller Institute identified phosphate in the protein Vitellin 1. In 1954, phosphorylation of a protein was observed when a liver enzyme catalyzed the phosphorylation of casein and became known as a protein kinase 2.  A year later, the role of phosphorylation became more interesting as Fischer and Krebs, and Wosilait and Sutherland 3, showed that an enzyme involved in glycogen metabolism was regulated by the addition or removal of a phosphate, suggesting that reversible phosphorylation could control enzyme activity. A peptide fragment of the thyroid hormone (TR)-binding protein (TRBP), the LXXLL motif, phosphorylated on Ser884 important for receptor selectivity and LXXLL-binding affinity correlates with TRBP transcriptional activity 4. Aquaporin - 2 (254 - 267), pSER256, human, a peptide fragment of the human aquaporin-2 (AQP2) phosphorylated at Ser256, plays a key role in vasopressin signaling in the renal-collecting duct 5.

Structural Characteristics

Phosphorylation refers to the addition of a phosphate to one of the amino acid side chains of a protein. Phosphates are negatively charged so that their addition to a protein leads to conformational change of the protein. Many bacterial species express 'eukaryotic-like' Ser/Thr or Tyr protein kinases and phosphatases that are candidate mediators of developmental changes and host/pathogen interactions. Studies reveal that universal mechanisms of regulation and substrate recognition govern the functions of prokaryotic and eukaryotic Ser/Thr protein kinases (STPKs). Several structures also support novel mechanisms of regulation, including dimerization of STPKs, metal-ion binding and substrate mimicry 6. There are several small peptides are involved in regulation of protein phosphorylation. Sequence of [pSer884] Thyroid Hormone Binding Protein (TRBP), biotin labeled is BIOTIN-KDVTLT(pSer)PLLVNLLQSDIS 4. Aquaporin - 2 (254 - 267), pSER256, human sequence is RQ-pS-VELHSPQSLPR. These peptides are used for thyroid hormone and vasopressin-dependent trafficking studies respectively 5.

Mode of Action

The transfer of phosphates onto proteins is catalyzed by a variety of protein kinases in the cell. The hydroxyl groups (-OH) of serine, threonine, tyrosine or histidine amino acid side chains are commonly used for addition of phosphate group. A second class of enzymes, phosphatases, are responsible for the reverse reaction, in which phosphates are removed from a protein. Some of these enzymes are extremely specific, potentially phosphorylating or dephosphorylating only a few target proteins, while others are able to act broadly on many proteins. The examples of known targets of phosphorylation include most protein components of the cell, including enzymes, structural proteins, cell receptors, ion channels and signaling molecules. If a protein is controlled by its phosphorylation state, its activity at any one time will be directly dependent on the activity of the kinases and phosphatases that act on it. It is quite common for a phosphate group to be added or removed from a protein continually, a cycle that allows a protein to switch rapidly from one state to another 7. [pSer884] Thyroid Hormone Binding Protein (TRBP) peptide interacts with nuclear receptors. Ligand-dependent interaction of nuclear receptors and co-activators is a critical step in nuclear receptor-mediated transcriptional regulation. Serine884 of TRBP LXXLL motif is a key residue for receptor selectivity 4. Aquaporins form pores in the membranes of cells and selectively pass water molecules through the membrane, and prevent the crossing of sodium, potassium and other ions and small molecules. Human aquaporin-2 (AQP2) peptide AQP2 residues including S256 and S261, are altered in response to vasopressin. In the presence of vasopressin, AQP2 monophosphorylated at Ser256 and diphosphorylated AQP2 (pSer256/261) increase in abundance, whereas AQP2 monophosphorylated at Ser261 decreases, suggesting that both sites are involved in vasopressin-dependent AQP2 trafficking 5.

Functions

Regulate cell processes, through the use of phosphorylation cycles and cascades, the cell is able to regulate a diverse set of processes, including cellular movement, reproduction and metabolism. It is the simplicity, reversibility and flexibility of phosphorylation that explains why it has been adopted as the most general control mechanism of the cell.

Signaling networks, the study of phosphorylated proteins combined with mass spectrometry have been used to identify and quantify dynamic changes in phosphorylated proteins over time. Systematic analysis of complex phosphorylation networks has helped in understanding of cellular processes8.

 PKC, C2 Domain (49 - 53), This peptide belongs to the C2 regulatory domain of e-protein kinase C, also known as e-PKC/V1. This peptide, used in studying the physiological role of isozymes, is most likely the PKC-selective activator and is found to be cardioprotective 9.

Regulatory functions, several enzymes and receptors are switched "on" or "off" by phosphorylation and dephosphorylation. Reversible phosphorylation results in a conformational change in the structure of enzymes and receptors, causing them to become activated or deactivated. Many phosphorylation related peptides act as a modulator of enzyme function 10.

References

1.     Levene PA, Alsberg CL (1906). The cleavage products of vitellin. JBC., 2(1):127–133.

2.     Pawson T (1994). Introduction: Protein Kinases. Faseb J., 8:1112-1113.

3.     Fischer EH, Krebs EG  (1955). Conversion of phosphorylase b to phosphorylase a in muscle extracts. JBC., 216: 121-132.

4.     Ko L, Cardona GR, Iwasaki T, Bramlett KS, Burris TP, Chin WW (2002). Ser-884 adjacent to the LXXLL motif of coactivator TRBP defines selectivity for ERs and TRs. Mol. Endocrinol., 16:128-132.

5.     Hoffert JD, Pisitkun T, Wang G, Shen RF, Knepper MA (2006). Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites. PNAS., 103(18):7159-7164.

6.     Greenstein AE, Grundner C, Echols N, Gay LM, Lombana TN, Miecskowski CA, Pullen KE, Sung PY, Alber T (2005). Structure/Function Studies of Ser/Thr and Tyr Protein Phosphorylation in Mycobacterium tuberculosis. J Mol Microbiol Biotechno., 9(3-4):167-181.

7.     Sefton BM, Hunter T (1998). Protein Phosphorylation. San Diego: Academic Press.

8.     Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. Cell, 127(3):635–648.

9.     Brandman R, Disatnik MH, Churchill E, Mochly-Rosen D (2007). Peptides derived from the C2 domain of protein kinase C epsilon (epsilon PKC) modulate epsilon PKC activity and identify potential protein-protein interaction surfaces. J. Biol. Chem., 282(6):4113-4123.

10.  Stock JB, Ninfa AJ, Stock AM (1989). Protein phosphorylation and regulation of adaptive responses in bacteria. Microbiol. Rev., 53(4):450–490.

 

 

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Product Name Catalog # Unit Price/Unit 
2B - (A)
Biotin-RRAAEELDSRAGAPQL
12983-01 1 mg $945 cart inquire
Abl Cytosolic Substrate
EAIYAAPFAKKK
13215-01 1 mg $828 cart inquire
Abltide
KKGEAIYAAPFA-CONH2
13273-01 1 mg $405 cart inquire
Abltide TAMRA - labeled
5-TAMRA-KKGEAIYAAPFA-CONH2
13274-01 1 mg $876 cart inquire
Abltide, FAM - labeled
5-FAM-KKGEAIYAAPFA-CONH2
13275-01 1 mg $1,317 cart inquire
ADR1 - derived peptide
LKKLTRRASFSGQ-OH
13304-01 1 mg $743 cart inquire
ADR1 - derived peptide, FAM - labeled
5-FAM-LKKLTRRASFSGQ-OH
13303-01 1 mg $1,317 cart inquire
AKT/PKB/Rac - Protein Kinase Substrate [ARKRERTYSFGHHA], 5 - FAM labeled
5-FAM-ARKRERTYSFGHHA
13067-01 1 mg $1,335 cart inquire
AKT/PKB/Rac - Protein Kinase Substrate [ARKRERTYSFGHHA], 5 - TMR labeled
5-TMR-ARKRERTYSFGHHA
13157-01 1 mg $1,436 cart inquire
AKT/PKB/Rac - Protein Kinase Substrate [ARKRERTYSFGHHA] Biotinylated
Biotin-ARKRERTYSFGHHA
13069-01 1 mg $467 cart inquire
Akt Specific Substrate Peptide, Akt/PKB
RPRAATF
13214-01 1 mg $828 cart inquire
Alternate Syntide
PLSRTLSVSSLPGL-CONH2
13257-01 1 mg $777 cart inquire
Alternate Syntide, FAM - labeled
5-FAM-PLSRTLSVSSLPGL-CONH2
13258-01 1 mg $1,335 cart inquire
AMARA peptide
AMARAASAAALARRR
13349-01 1 mg $405 cart inquire
AMPKtide, FAM - labeled
5-FAM-LKKLTRRASFSAQ
13272-01 1 mg $1,317 cart inquire
Aquaporin - 2 (254 - 267), human
RQSVELHSPQSLPR
13236-01 1 mg $743 cart inquire
Aquaporin - 2 (254 - 267), pSER256, human
RQ-pS-VELHSPQSLPR
13237-01 1 mg $863 cart inquire
Aquaporin - 2 (254 - 267), pSER261, human
RQSVELH-pS-PQSLPR
13240-01 1 mg $863 cart inquire
Aquaporin - 2 (255 - 271), human
QSVELHSPQSLPRGSKA
13238-01 1 mg $795 cart inquire
Aquaporin - 2 (255 - 271), rat
QSVELHSPQSLPRGTKA
13239-01 1 mg $795 cart inquire
Autocamtide - 2 [KKALRRQETVDAL]
KKALRRQETVDAL
13138-01 1 mg $728 cart inquire
Autocamtide - 2 [KKALRRQETVDAL], 5 - FAM labeled
5-FAM-KKALRRQETVDAL
13056-01 1 mg $1,335 cart inquire
Autocamtide - 2 [KKALRRQETVDAL], 5 - TMR labeled
5-TMR-KKALRRQETVDAL
13057-01 1 mg $1,436 cart inquire
Autocamtide - 2 [KKALRRQETVDAL], Biotinylated
Biotin-KKALRRQETVDAL
13055-01 1 mg $998 cart inquire
Autocamtide - 2 [KKALRRQETVDAL], Phosphorylated
KKALRRQE-pT-VDAL
13054-01 1 mg $1,098 cart inquire
Autocamtide - 3 [KKALHRQE - pT - VDAL], Phosphorylated
KKALHRQE-pT-VDAL
13092-01 1 mg $1,047 cart inquire
Autocamtide - 3 [KKALHRQETVDAL]
KKALHRQETVDAL
13091-01 1 mg $795 cart inquire
Autocamtide - 3 [KKALHRQETVDAL], 5 - FAM labeled
5-FAM-KKALHRQETVDAL
13095-01 1 mg $1,317 cart inquire
Autocamtide - 3 [KKALHRQETVDAL], 5 - TMR labeled
5-TMR-KKALHRQETVDAL
13094-01 1 mg $1,452 cart inquire
Biotin - IkB Inhibitor, amide
Biotin-DRHDSGLDSMKD-CONH2
13128-01 1 mg $998 cart inquire
Biotin - LC - PKG Substrate 1
Biotin-LC-QKRPRRKDTP
13029-01 1 mg $980 cart inquire
Biotin - LC - Translation Initiation Factor 2B
Biotin-LC-RRAAEELDSRAGpSPQL
13136-01 1 mg $1,133 cart inquire
Biotin - PLSRTL - pS - VASLPGL - NH2
Biotin-PLSRTL-pS-VASLPGL-CONH2
13026-01 1 mg $1,013 cart inquire
Biotin - Tyrosine Kinase Peptide 1, amide
Biotin-KVEKIGEGTYGVVYK-CONH2
12989-01 1 mg $1,047 cart inquire
Bovine ß - Casein monophosphopeptide
FQ-pS-EEQQQTEDELQDK
13224-01 1 mg $521 cart inquire
BPDEtide [RKISASEFDRPLR]
RKISASEFDRPLR
13158-01 1 mg $828 cart inquire
BPDEtide [RKISASEFDRPLR], 5 - FAM labeled
5-FAM-RKISASEFDRPLR
13159-01 1 mg $1,335 cart inquire
BPDEtide [RKISASEFDRPLR], 5 - TMR labeled
5-TMR-RKISASEFDRPLR
13160-01 1 mg $1,470 cart inquire
BPDEtide [RKISASEFDRPLR], Biotinylated
Biotin-RKISASEFDRPLR
13161-01 1 mg $1,166 cart inquire
BTK derived peptide
KKVVALYDYMPMN-CONH2
13253-01 1 mg $777 cart inquire
BTK derived peptide, FAM - labeled
5-FAM-KKVVALYDYMPMN-CONH2
13254-01 1 mg $1,317 cart inquire
ε - C2/V1 (49 - 53), ε PKC, C2 Domain (49 - 53)
SRIGQ
13333-01 1 mg $675 cart inquire
ε - C2/V1, ε PKC, C2 Domain (119 - 124)
LEPEGK
13334-01 1 mg $693 cart inquire
Calcineurin Autoinhibitory Fragment
ITSFEEAKGLDRINERMPPRRDAMP
12991-01 1 mg $1,013 cart inquire
Calcineurin (PP2B) Substrate [DLDVPIPGRFDRRV - pS - VAAE], 5 - FAM labeled
5-FAM-DLDVPIPGRFDRRV-pS-VAAE
13081-01 1 mg $1,520 cart inquire
Calcineurin (PP2B) Substrate [DLDVPIPGRFDRRV - pS - VAAE], 5 - TMR labeled
5-TMR-DLDVPIPGRFDRRV-pS-VAAE
13082-01 1 mg $1,673 cart inquire
Calcineurin (PP2B) Substrate [DLDVPIPGRFDRRV - pS - VAAE], Biotinylated
Biotin-DLDVPIPGRFDRRV-pS-VAAE
13080-01 1 mg $1,485 cart inquire
Calcium/Calmodulin Dependent Protein Kinase II - g (345 - 358)
KSDGGVKKRKSSSS
12962-01 1 mg $761 cart inquire
Calmodulin - Dependent Protein Kinase II (281 - 289)
MHRQETVDC
12946-01 1 mg $608 cart inquire
Calmodulin - Dependent Protein Kinase II (281 - 309)
MHRQETVDCLKKFNARRKLKGAILTTMLA
12947-01 1 mg $1,047 cart inquire
Calmodulin - Dependent Protein Kinase II (290 - 309)
LKKFNARRKLKGAILTTMLA
12943-01 1 mg $845 cart inquire
CaM Kinase II Substrate 281 - 291 [MHRQE - pT - VDCLK - NH2], Phosphorylated
MHRQE-pT-VDCLK-CONH2
13079-01 1 mg $1,013 cart inquire
CaM Kinase II Substrate 281 - 291 [MHRQETVDCLK - NH2], 5 - FAM labeled
5-FAM-MHRQETVDCLK-CONH2
13077-01 1 mg $1,317 cart inquire
CaM Kinase II Substrate 281 - 291 [MHRQETVDCLK - NH2], 5 - TMR labeled
5-TMR-MHRQETVDCLK-CONH2
13076-01 1 mg $1,452 cart inquire
CaM Kinase II Substrate 281 - 291 [MHRQETVDCLK - NH2], Biotinylated
Biotin-MHRQETVDCLK-NH2
13078-01 1 mg $980 cart inquire
cAMP - Dependent Protein Kinase Inhibitor (5 - 22), amide, Wiptide
TTYADFIASGRTGRRNAI-CONH2
12945-01 1 mg $710 cart inquire
cAMP - Dependent Protein Kinase Inhibitor, PKI - tide
IAAGRTGRRQAIHDILVAA
12944-01 1 mg $710 cart inquire
cAMP Dependent Protein Kinase Substrate
RRKASGP
12959-01 1 mg $608 cart inquire
Casein Kinase II Receptor Peptide
RREEETEEE
12948-01 1 mg $642 cart inquire
Casein Kinase II Substrate
RRREEETEEE
12999-01 1 mg $777 cart inquire
Casein Kinase II Substrate [RRADDSDDDDD], 5 - FAM labeled
5-FAM-RRADDSDDDDD
13189-01 1 mg $1,335 cart inquire
Casein Kinase II Substrate [RRADDSDDDDD], 5 - TMR labeled
5-TMR-RRADDSDDDDD
13190-01 1 mg $1,470 cart inquire
Casein Kinase II Substrate [RRADDSDDDDD], Biotinylated
Biotin-RRADDSDDDDD
13191-01 1 mg $998 cart inquire
Casein Kinase II Substrate [RRADDSDDDDD], Phosphorylated
RRADD-pS-DDDDD
13192-01 1 mg $1,166 cart inquire
Casein Kinase I Substrate [RRKDLHDDEEDEAMSITA]
RRKDLHDDEEDEAMSITA
13198-01 1 mg $828 cart inquire
Casein Kinase I Substrate [RRKDLHDDEEDEAMSITA], 5 - FAM labeled
5-FAM-RRKDLHDDEEDEAMSITA
13199-01 1 mg $1,335 cart inquire
Casein Kinase I Substrate [RRKDLHDDEEDEAMSITA], 5 - TMR labeled
5-TMR-RRKDLHDDEEDEAMSITA
13200-01 1 mg $1,436 cart inquire
Casein Kinase I Substrate [RRKDLHDDEEDEAMSITA], Biotinylated
Biotin-RRKDLHDDEEDEAMSITA
13201-01 1 mg $1,098 cart inquire
Cathepsin D and E FRET Substrate
Mca - GKPILFFRLK(Dnp) - r - NH2
14524-01 1 mg $467 cart inquire
Cathepsin K substrate
Abz - HPGGPQ - EDDnp
14831-001 0.1 mg $405 cart inquire
CDC25C
KKKVSRSGLYRSPSMPENLNRPR
13218-01 1 mg $1,335 cart inquire
CDc25C - derived peptide, FAM - labeled
5-FAM-VSRSGLYRSPSMPENLNRPR-OH
13252-01 1 mg $1,250 cart inquire
CDK5 Substrate [PKTPKKAKKL], 5 - FAM labeled
5-FAM-PKTPKKAKKL
13098-01 1 mg $1,115 cart inquire
CDK5 Substrate [PKTPKKAKKL], 5 - TMR labeled
5-TMR-PKTPKKAKKL
13099-01 1 mg $1,233 cart inquire
CDK5 Substrate [PKTPKKAKKL], Biotinylated
Biotin-PKTPKKAKKL
13118-01 1 mg $810 cart inquire
CDK7/9 tide
YSPTSPSYSPTSPSYSPTSPSKKKK
14832-01 1 mg $653 cart inquire
CDK7tide
YSPTSPSYSPTSPSYSPTSPS
13282-01 1 mg $912 cart inquire
CDK7tide derived peptide, FAM - labeled
5-FAM-FLAKSFGSPNRAYKK-OH
13284-01 1 mg $1,166 cart inquire
CDK7tide, TAMRA labeled
5-TAMRA-YSPTSPSYSPTSPSYSPTSPS
13283-01 1 mg $1,335 cart inquire
CDPKS, Syntide analog
PLRRTLSVAA
13263-01 1 mg $761 cart inquire
CK1tide
HAAIGDDDDAYSITS-CONH2
13290-01 1 mg $761 cart inquire
CK1tide
5-TAMRA-HAAIGDDDDAYSITS-CONH2
13291-01 1 mg $1,233 cart inquire
CK2tide, FAM - labeled
5-FAM-RRRADDSDDDDD-CONH2
13294-01 1 mg $1,148 cart inquire
CREB2 (91 - 116)
ESEDSQESVDSVTDSQKRREILSRRP
13229-01 1 mg $1,098 cart inquire
CREB327 (113 - 126)
ILSRRPSYRKILND
13230-01 1 mg $777 cart inquire
CREBtide
GEILSRRPSYRK-CONH2
13292-01 1 mg $710 cart inquire
CREBtide, FAM - labeled
5-FAM-GEILSRRPSYRK-CONH2
13293-01 1 mg $1,115 cart inquire
CREBtide [KRREILSRRPSYR]
KRREILSRRPSYR
13162-01 1 mg $828 cart inquire
CREBtide [KRREILSRRPSYR] 5 - FAM labeled
5-FAM-KRREILSRRPSYR
13154-01 1 mg $3,308 cart inquire
CREBtide [KRREILSRRPSYR], Biotinylated
Biotin-KRREILSRRPSYR
12988-01 1 mg $998 cart inquire
CREBtide [KRREILSRRPSYR] Phosphorylated C - term
KRREILSRRPS-pY-RK
12224-01 1 mg $635 cart inquire
CREBtide [KRREILSRRPSYR], Phosphorylated, C - term KC
KRREILSRRP-pS-YRKC
13036-01 1 mg $1,047 cart inquire
Crosstide [GRPRTSSFAEG]
GRPRTSSFAEG
13124-01 1 mg $932 cart inquire
Crosstide [GRPRTSSFAEG], 5 - FAM labeled
5-FAM-GRPRTSSFAEG
13153-01 1 mg $1,166 cart inquire
Crosstide [GRPRTSSFAEG], 5 - TMR labeled
5-TMR-GRPRTSSFAEG
13139-01 1 mg $1,335 cart inquire
Crosstide [GRPRTSSFAEG], Biotinylated
Biotin-GRPRTSSFAEG
13165-01 1 mg $998 cart inquire
CT11 - F, FAM labeled
5-FAM-DLLRCRVLTSG
13314-01 1 mg $1,098 cart inquire
DAM1 [221 - 241] peptide
SFVLNPTNIGM-pS-KSSQGHVTK
13228-01 1 mg $1,115 cart inquire
delta PKC (8 - 17) PKC d Inhibitor
SFNSYELGSL
14423-01 1 mg $405 cart inquire
Dictyostelium Myosin II Heavy Chain, MH - 1 (2020 - 2035)
RKKFGESEKTKTKEFL
13322-01 1 mg $777 cart inquire
DNA - PK Substrate
EPPLSQEAFADLWKK
13125-01 1 mg $761 cart inquire
Dominant H2 - Kd Ligand
SYFPEITHI
13347-01 1 mg $710 cart inquire
EGFR (988 - 993), Amide, Phosphorylated
DADE-pY-L-CONH2
13211-01 1 mg $845 cart inquire
EGFR (988 - 993), Phosphorylated
DADE-pY-L
13220-01 1 mg $1,215 cart inquire
EGFR - derived peptide
LVEPLTPSGEAPNQK-OH
13310-01 1 mg $761 cart inquire
EGFR - derived peptide, FAM labeled
LVEPLTPSGEAPNQ-K(5-FAM)-OH
13308-01 1 mg $1,233 cart inquire
EGFR - derived Peptide, TAMRA labeled
LVEPLTPSGEAPNQ-K(5-TAMRA)-CONH2
13309-01 1 mg $1,335 cart inquire
EGF Receptor 661 - 681 [KRELVEPL - pT - PSGEAPNQALLR - NH2], Phosphorylated
KRELVEPL-pT-PSGEAPNQALLR-CONH2
13083-01 1 mg $1,335 cart inquire
EGF Receptor 661 - 681 [KRELVEPLTPSGEAPNQALLR - NH2]
KRELVEPLTPSGEAPNQALLR-CONH2
13087-01 1 mg $1,080 cart inquire
EGF Receptor 661 - 681 [KRELVEPLTPSGEAPNQALLR - NH2], 5 - FAM labeled
5-FAM-KRELVEPLTPSGEAPNQALLR-CONH2
13086-01 1 mg $1,317 cart inquire
EGF Receptor 661 - 681 [KRELVEPLTPSGEAPNQALLR - NH2], 5 - TMR labeled
5-TMR-KRELVEPLTPSGEAPNQALLR-CONH2
13085-01 1 mg $1,485 cart inquire
EGF Receptor 661 - 681 [KRELVEPLTPSGEAPNQALLR - NH2], Biotinylated
Biotin-KRELVEPLTPSGEAPNQALLR-CONH2
13084-01 1 mg $1,148 cart inquire
EGF Receptor Substrate 2 [DADE - pY - LIPQQG] 5 - FAM labeled
5 - FAM - DADE - pY - LIPQQG
14833-01 1 mg $4,085 cart inquire
EGF Receptor Substrate 2 [DADE - pY - LIPQQG] Biotinylated
Biotin - DADE - pY - LIPQQG
14834-01 1 mg $669 cart inquire
EGF Receptor Substrate 2 [DADE - pY - LIPQQG]
DADE-pY-LIPQQG
12995-01 1 mg $1,148 cart inquire
EGF Receptor Substrate 2 [DADE - pY - LIPQQG] 5 - FAM labeled
5-FAM-DADE-pY-LIPQQG
13089-01 1 mg $669 cart inquire
EGF Receptor Substrate 2 [DADE - pY - LIPQQG], 5 - TMR labeled
5-TMR-DADE-pY-LIPQQG
13088-01 1 mg $1,485 cart inquire
EGF Receptor Substrate 2 [DADE - pY - LIPQQG], C - term FF
DADE-pY-LIPQQGFF
12994-01 1 mg $1,166 cart inquire
EGFR Protein Tyrosine Kinase Substrate [ADEYLIPQQ], 5 - FAM labeled
5-FAM-ADEYLIPQQ
13065-01 1 mg $1,133 cart inquire
EGFR Protein Tyrosine Kinase Substrate [ADEYLIPQQ], 5 - TMR labeled
5-TMR-ADEYLIPQQ
13064-01 1 mg $1,283 cart inquire
EGFR Protein Tyrosine Kinase Substrate [ADEYLIPQQ], Biotinylated
Biotin-ADEYLIPQQ
13061-01 1 mg $1,013 cart inquire
Epsilon - C2/V1(74 - 79), epsilon PKC (74 - 79), C2 Domain
CNGRKI
13332-01 1 mg $693 cart inquire
epsilon - V1 - 2 epsilon - PKC Inhibitor Cys - conjugated
EAVSLKPTC
13335-01 1 mg $405 cart inquire
Epsilon - V1 - 2, epsilon - PKC Specific Inhibitor
CEAVSLKPT
13338-01 1 mg $710 cart inquire
ERK 1/2 /MAP Kinase Substrate, FAM labeled
5-FAM-IPTSPITTTYFFFKKK
13340-01 1 mg $1,182 cart inquire
ERKtide
ATGPLSPGPFGRR
13126-01 1 mg $728 cart inquire
Erktide
IPTTPITTTYFFFK
13297-01 1 mg $405 cart inquire
Erktide, FAM - labeled
IPTTPITTTYFFF-K (5-FAM)-OH
13298-01 1 mg $1,166 cart inquire
FceRI gamma - chain ITAM - Derived Phosphopeptide, TAMRA labeled
5-TAMRA-pY-TGLSTRNQET-pY-ETL-CONH2
13296-01 1 mg $1,790 cart inquire
FCeRI g - chain ITAM - derived phospho peptide, FAM labeled
5-FAM-pY-TGLSTRNQET-pY-ETL-CONH2
13295-01 1 mg $1,722 cart inquire
Forkhead derived peptide, FAM - labeled, Woodtide
5-FAM-KKISGRLSPIMTEQ-CONH2
13269-01 1 mg $1,182 cart inquire
Forkhead derived peptide, Woodtide
KKISGRLSPIMTEQ-CONH2
13268-01 1 mg $405 cart inquire
Gastrin derived peptide, FAM - labeled
5-FAM-GPWLEEEEEAYGWMDFK-CONH2
13270-01 1 mg $1,215 cart inquire
Generic Protein Kinase Substrate
RARTLSFAEPG
13317-01 1 mg $710 cart inquire
Glycogen Synthase 1 - 10 5 - FAM labeled
5-FAM-PLSRTLSVSS-NH2
14492-01 1 mg $818 cart inquire
Glycogen Synthase 1 - 10 [PLSRTLSVSS - NH2]
PLSRTLSVSS-CONH2
13166-01 1 mg $828 cart inquire
Glycogen Synthase 1 - 10 [PLSRTLSVSS - NH2], 5 - FAM labeled
5-FAM-PLSRTLSVSS-CONH2
13167-01 1 mg $1,166 cart inquire
Glycogen Synthase 1 - 10 [PLSRTLSVSS - NH2], 5 - TMR labeled
5-TMR-PLSRTLSVSS-CONH2
13168-01 1 mg $1,335 cart inquire
Glycogen Synthase 1 - 10 [PLSRTLSVSS - NH2], Biotinylated
Biotin-PLSRTLSVSS-CONH2
13169-01 1 mg $998 cart inquire
Glycogen Synthase 1 - 8 [PLSRTLSVAAKK - NH2]
PLSRTLSVAAKK-CONH2
13025-01 1 mg $728 cart inquire
Glycogen Synthase 1 - 8 [PLSRTLSVAAKK - NH2]
PLSRTLSVAAKK
12971-01 1 mg $608 cart inquire
Glycogen Synthase 1 - 8 [PLSRTLSVAAKK - NH2], 5 - FAM labeled
5-FAM-PLSRTLSVAAKK-CONH2
13038-01 1 mg $1,115