Custom Oligonucleotide Dendrimer Services
Two strategies for the synthesis of oligonucleotide dendrimers are possible: Divergent
- with the structure growing from the center to the periphery; and Convergent -
with growth from the periphery to the center. The number of branches generated at
each step determines the number of repetitive steps necessary to build up the desired
molecule and the density of groups at the periphery. The groups or moieties on its
outer shell determine the properties of the molecule. The dendrimeric modifiers
we use permit the synthesis of a dendrimeric structure on top of a conventional
monomeric oligonculeotide, as well as directly on the solid support at 3' end. The
monomeric and the dendrimeric sequence segments can be prepared with different lengths
and different orientation by using 3' or 5' oligonucleotide synthesis chemistry.
Due to complexity of the construct, please contact us
for pricing
Symmetric Doubler 2DNA
The symmetric doubler produces branches with the same oligo sequence.
Symmetric Trebler 3DNA
The symmetric doubler produces branches with the same oligo sequence
Different generations of dendrimeric oligonucleotides
