Bio-Synthesis offers Cyan 500 oligonucleotide labeling. This amine-reactive fluorescent label can be incorporate to an oligo at 5', 3' and internally. Cyan 500 is designed and recommended by Roche for application in LightCycler® instruments. The dye can be incorporate to a functionalized oligonucleotide through cross linking chemistry. Cyan500 labeled oligo can be detected on excitation at 430 nm in Roche LightCycler® instruments. Cyan 500 NHS-Ester can also be used as label for other bio-molecules such as proteins etc. The dye has Molecular Weight 580 g/mol and is moderately hydrophilic.

This dye can combine with BBQ, BlackBerry Quencher, Dabcyl, BHQ-1 or our Instant Quencher (IQ4). We also offer Cyan500 replacement dye labeling.

Dye ABS [nm] EM [nm] Repalcement dye ABS [nm] EM [nm]
CY480 Cyan 500
ATTO 425 436 484
ATTO 465 453 508

Contact Bio-Synthesis for Cyan 500 Oligo Labeling Services. 

Product Information


Product Name:

Cyan 500 NHS


Fluorescent dye, LightCycler

Modification Code:


Formula Weight:


Absorption λmax:

436 nm

Extinction Coefficient, ε(λ):

45000 I/mol cm


Bio-Synthesis Inc. Oligo Structure



Delivery Format:


Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.