Alkoxyamine is an aminooxy 11 modifier which contains a tetraethylene glycol linkage. Alkoxyamine is an aldehyde or ketone reactive group forming stable oximes conjugate with improved solubility and has minimal effects on hybridization of the oligo.This reactive group is commonly used in biomolecule probes for labeling and crosslinking carbonyls (oxidized carbohydrates) on glycoproteins and other polysaacharides under physiological conditions. Although aldehydes do not naturally occur in proteins or other macromolecules, they can be easily created through an oxidizable sugar group that is commonly found in polysaccharide, glycoprotein or ribos of RNA.  The manufacturing of hydrazide modified oligonucleotide can be achieve at the 5' or 3' end using reverse synthesis chemistry.

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Product Information


Product Name:

Alkoxyamine Modified Oligonucleotide

Alternate Name:




Modification Code:


Formula Weight:



Bio-Synthesis Inc. Oligo Structure



Delivery Format:


Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.