Amino TEG Modified Oligonucleotide

Amino TEG oligonucleotide modifer, a hydrophilic triethylene glycol ethylamine derivative, is a chemical modification that allows the functionalizing of oligonucleotides at the 5'-terminal end. 5'-Amino-modifier oligonucleotides are valuable tools in molecular biology, enabling a wide range of experimental and therapeutic strategies.

Adding an amino group to the 5'-end enhances the oligonucleotide's functionality and allows its use in various applications.

Oligonucleotides modified with a 5'-amino group make the following possible:

• Conjugation: An amino group at the 5'-end allows attaching other molecules, such as fluorescent dyes, biotin, or peptides, enabling versatile labeling or functionalization.
• Increased Stability: Modifying the 5'-end can improve the stability of oligonucleotides against enzymatic degradation.
• Enhanced Binding: The amino modifier enables the addition of other functionalities that can influence hybridization properties and potentially improve binding affinity to target sequences.
• Bioactivity: Amino group-modified oligonucleotides allow the design to facilitate interactions with proteins or other biomolecules, making them useful in therapeutic or diagnostic applications.

Product Information

 

Product Name:

Amino TEG Modified Oligonucleotide

Alternate Name:

Amino TEG

Category:

cross linker

Modification Code:

[Amino TEG]

Structure:

Purification:

HPLC or PAGE

Delivery Format:

Lyophilized

Shipping Conditions:

Room Temperature

Storage Conditions:

-20°C To -70°C
Oligonucleotides are stable in solution at 4°C for up to 2 weeks. Properly reconstituted material stored at -20°C should be stable for at least 6 months. Dried DNA (when kept at -20°C) in a nuclease-free environment should be stable for years.

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References/Citations:

Technical & Educational

Frequently Asked Questions

Scientific Literature

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