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High Resolution HLA Analysis in situations of Marker(STRs) Depletion

Introduction
The Human Leukocyte Antigen (HLA) is one of the most polymorphic gene systems known in humans, comprising of over 1000 alleles over the Class I (A, B and C) and Class II (DR, DQ and DP). In fact HLA was used early (since the 70’s) to determine paternity in the USA and the worldwide.