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High Resolution HLA Analysis in Situations of STR Marker Depletion

The Human Leukocyte Antigen (HLA) molecules are cell-surface proteins found in most cells in the human body (except red blood cells). HLA has one of the most polymorphic gene systems, comprising over 1000 alleles in the Class I (A, B and C) and Class II (DR, DQ and DP). In fact, HLA typing has been used since 1970s to determine paternity in the USA and worldwide. Therefore, HLA typing method is an excellent addition for DNA testing.