Do you offer ferrocene peptide conjugation?
Bio-Synthesis offers ferrocene peptide conjugates for electrochemical studies. These ferrocene and ferrocene derivatives can be conjugated to peptides post-synthetically using an appropriate cross linking chemistry such as NHS ester. Ferrocene peptide conjugates require dual purification. The specific ferrocene conjugate products can be chosen based on desired physical properties. Organometallic reagents with high electron transfer properties improve stability in diesel fuels and provide very efficient backbones for phosphine ligands. We offer two types of peptide ferrocene conjugation 1)Ferrocene-amidopentyl (Ferrocene-C6) 2) Ferrocene. These ferrocene-peptide conjugates have been designed to induce highly ordered structures of peptides and develop new biomaterials. The ferrocene serves as a reliable organometallic scaffold for the construction of an ordered structure via intramolecular hydrogen bonding, wherein the attached peptide strands are regulated in appropriate dimensions. Another noteworthy feature of ferrocene–peptide bioconjugates is their strong tendency to self-assemble through the contribution of available hydrogen bonding sites in the solid state. Furthermore, the ferrocene moiety of ferrocene–peptide bioconjugates is able to act as a redox-switching center and an electrophore in the receptors and biomaterials.
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07/24/2013