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Oligonucleotide

Can a branched divalent siRNA target the central nervous system?

07/28/2026

Does increasing the length of a ssDNA from 47 nts to approximately 80–100 nts improve circularization efficiency, purification, or separation from a linear precursor?

07/13/2026

How should the final lyophilized circular ssDNA be resuspended and stored?

07/13/2026

What circularization method is used for the production of circular oligonucleotides?

07/13/2026

Can you please confirm whether the final quoted quantity refers to purified circular ssDNA only, rather than total crude or total recovered material?

07/13/2026

Is ESI-MS or another mass-based confirmation analysis available or recommended to verify the quality of our products?

07/13/2026

What is an Exonuclease I (Exo I)-resistance Quality Control (QC) Assay?

07/13/2026

What is Exonuclease I (Exo I)-resistance?

07/13/2026

Do you provide QC data that specifically helps distinguish circular ssDNA from linear ssDNA, such as a PAGE image, PAGE densitometry, CE/HPLC trace, or another suitable method?

07/08/2026

What level of residual linear ssDNA precursor can be expect in the final product?

07/08/2026

For circular single-stranded DNA, does the stated purity in a COA refer specifically to the percentage of circular ssDNA in the final product?

07/08/2026

How do RUO, GLP, and GMP oligonucleotides compare?

05/21/2026

What are GMP-grade oligonucleotides?

05/21/2026

What are GLP-grade oligonucleotides?

05/21/2026

What are research-grade oligonucleotides or RUO oligos

05/21/2026

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