New nucleic acid diagnostic tool with enhanced hybridization and quantification power.
Shivarov et al. published their work using BNA-NC probes allowed for the quantitative and sensitive detection of different mutant alleles. This rapid, easy and reliable diagnostic method is expected to allow the detection of myeloid malignancies. View Video
Deimination reaction of arginyl residues within peptide bonds Deimination of arginine results in neutral citrulline with the release of ammonia and the loss of one positive charge for each arginyl residue deiminated. The process is catalyzed by a calcium dependent peptidylarginine deiminase.
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