Yes, Bio-Synthesis a supplier of double dye labeled oligonucleotide probes. we offer large combination of fluorescent reporter dye and quenchers. qPCR probe or double-dye oligonucleotide are designed to anneal with PCR primers, therefore, when designing probes, be sure your tm must be higher than the upstream primer. In corporation of modified base such as BNA can be use to modulate Tm and enhance specificity. All our double-dye oligonucleotide probe are HPLC purified with guarantee >95% pure. They are quality checked by analytical HPLC and mass spectrometry. These double-dye oligonucleotide probes are delivered lyophilized in individual tubes.