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What steps do you take to assure the cells that you test are authentic?

If the genotypes for parental cells already have been determined by a recognized repository (ATCC, DSMZ, or JCRB) the genotype of the submitted cells can be compared to genotypes in the database. Comparison of the genetic profile of the sample generated by short tandem repeat analysis (STR) to the known profile of the cell line allows verification of the authenticity of the cell line. The diversity of alleles, repeating segments of DNA 2 to 6 base pairs in length that have a diverse number of repeats at a single locus, makes it possible to generate unique genetic profiles by combining analysis results for a number of marker loci. To determine gender the amelogenin marker found on the X and Y chromosome is routinely used.