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Why tryptophan analysis is important?

  1. Tryptophan (Trp, W) is an essential amino acid for humans and is needed for multiple biological functions
  2. Tryptophan (Trp, W) present in many proteins and important in human nutrition for establishing and maintaining a positive nitrogen balance
  3. Trp is the precursor of the neurotransmitter serotonin and needed in brain functions and related regulatory mechanisms
  4. Trp is an important, frequently used starting material in the chemical synthesis of a wide range of pharmaceuticals
  5. Trp has been used in the treatment of depression, schizophrenia, and hypertension
  6. Trp derivatives are potent drugs
  7. Trp is widely used in the food industry and is sometimes added to dietary and feed products as a food fortifier in order to maintain amino acid balance and correct possible dietary deficiencies.
  8. Trp can also be used to study structure and dynamics of protein because of its indole moiety and unique spectrophotic behavior
  9. The nutritional and biochemical importance of Trp emphasizes the need for reliable analytical methods for the determination of Trp in food and feed proteins.