Why tryptophan analysis is important?
- Tryptophan (Trp, W) is an essential amino acid for humans and is needed for multiple biological functions
- Tryptophan (Trp, W) present in many proteins and important in human nutrition for establishing and maintaining a positive nitrogen balance
- Trp is the precursor of the neurotransmitter serotonin and needed in brain functions and related regulatory mechanisms
- Trp is an important, frequently used starting material in the chemical synthesis of a wide range of pharmaceuticals
- Trp has been used in the treatment of depression, schizophrenia, and hypertension
- Trp derivatives are potent drugs
- Trp is widely used in the food industry and is sometimes added to dietary and feed products as a food fortifier in order to maintain amino acid balance and correct possible dietary deficiencies.
- Trp can also be used to study structure and dynamics of protein because of its indole moiety and unique spectrophotic behavior
- The nutritional and biochemical importance of Trp emphasizes the need for reliable analytical methods for the determination of Trp in food and feed proteins.