PNA Synthesis Overview

Custom PNA Oligomer Synthesis

Bio-Synthesis provides fast and high-quality custom peptide nucleic acid (PNA) synthesis services and reagents through the use of automated robotics synthesis platforms and cutting-edge chemistries. Our end-to-end system is design to deliver quality peptide nucleic acid (PNA) reagents that are used as tools in several applications such as:

• Antisense and antigen therapy
• miRNA inhibitors
• Molecular probes for diagnostics and detection
• Tools for molecular biology and functional genomics

BSI delivers quality Peptide Nucleic Acid (PNA) probes that are synthesized to your specifications. As always, every custom oligonucleotide synthesis is deprotected and desalted.

Newer generation DNA/RNA mimics:

• BNA3 (Bridged Nucleic Acids)
• Zip Nucleic Acids (ZNA®) Oligospermine Conjugates
• GNA (Glycerol Nucleic Acids)
• ENA (2'-O,4'-C-ethylene-bridged nucleic acid)
• Morpholino
• Peptide nucleic acid bioconjugate

Bio-Synthesis is introducing "BNA3" - A third generation multi functional bridged nucleic acid with stronger and more specific binding affintiy and nuclease resistance.

• Greater affinity and sequence specificity than conventional PNAs
• Greater strand invasion to any sequences from 0 to 100% G/C content
• Permit functionalization
• Multiple labeling capability
• Improved cell penetration and cellular uptake
• Stronger resistance to enzyme digestion
• Water soluable and no issue with aggregation
• Ideal for FISH probe, miRNA, drug discovery and nanotechnology.

Learn more about BNA3 oligo synthesis.