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Custom antibody nanoparticle conjugation and nanoparticle bioconjugation for gold nanoparticles, magnetic particles, quantum dots, silica nanoparticles, and polymer nanoparticles. Antibody-functionalized nanoparticle conjugates are designed for diagnostics, biosensing, imaging, capture and separation, and targeted delivery applications.
Antibody nanoparticle conjugation combines the molecular specificity of antibodies with the functional properties of nanoparticles to create advanced materials for detection, imaging, capture, separation, and targeted delivery. Through custom nanoparticle conjugation and antibody labeling of nanoparticles, the final conjugate can be tailored for optical readout, magnetic handling, fluorescent signaling, biosensing, or delivery-oriented workflows.
Different nanoparticle systems bring different functional advantages. Gold nanoparticles support colorimetric detection and lateral flow systems, magnetic particles enable separation and enrichment, quantum dots provide fluorescent imaging capability, and polymer or silica nanoparticles can be used for engineered delivery and surface-functionalized analytical workflows.
Built around the final application: The best nanoparticle conjugation strategy depends on particle type, surface chemistry, antibody format, stability requirements, signal readout, and whether the goal is detection, separation, imaging, or delivery.
Platforms
Optical to magnetic
Support for gold, magnetic, fluorescent, silica, and polymer nanoparticle systems
Formats
IgG, IgM, and fragments
Whole antibodies, IgG, IgM, fragments, and secondary probe formats can be supported
Use Cases
Detection to delivery
Useful for diagnostics, biosensing, capture, enrichment, imaging, and targeted delivery
Approach
Application-specific
Conjugation strategy aligned to nanoparticle surface chemistry and intended performance
Antibody nanoparticle conjugation can be applied to multiple antibody and probe formats depending on the intended assay design, imaging method, particle system, and downstream workflow.
Antibody–nanoparticle conjugation of full-length antibodies for diagnostics, biosensing, targeting, separation, and analytical workflows.
Nanoparticle conjugation of IgG antibodies for routine immunoassays, imaging, magnetic separation, and targeted particle systems.
Support for IgM conjugation when this antibody class is required for the final analytical or targeting workflow.
Conjugation of Fab, F(ab')2, and related fragment formats for reduced steric hindrance, altered Fc behavior, or particle surface optimization.
Particle conjugation of primary antibodies for direct target recognition in detection, imaging, and targeted delivery systems.
Nanoparticle-conjugated secondary reagents for indirect detection, signal amplification, and specialized assay architecture.
One service, multiple compatible formats: These are not separate services. They are the antibody and probe formats that can be used within the broader antibody nanoparticle conjugation service.
Widely used in lateral flow assays, colorimetric detection, biosensors, and analytical systems that benefit from strong optical properties.
Support magnetic separation, capture, enrichment, sample handling, and automation workflows in assay and diagnostic systems.
Fluorescent nanoparticle systems used for multiplex imaging, long-lived signal generation, and sensitive optical detection workflows.
Stable surface-functionalizable particles used in analytical platforms, biosensing, and imaging-related applications.
Useful for delivery systems, encapsulation strategies, engineered surface presentation, and targeted biological applications.
Conjugation strategy can be aligned to specialized or custom particle formats depending on the final use case and surface chemistry.
We select the optimal chemistry based on nanoparticle type, antibody format, application requirements, and the desired performance of the final nanoparticle antibody conjugate.
Passive adsorption via electrostatic and hydrophobic interactions for gold nanoparticles.
Stable amide bond formation for strong and reliable antibody conjugation.
Bioorthogonal conjugation for precise orientation and high efficiency.
A variety of linkers for controlled spacing and improved functionality.
Why chemistry matters: Conjugation chemistry affects particle stability, antibody orientation, binding activity, surface accessibility, signal performance, and the final behavior of the conjugate in the intended system.
Select the most suitable particle system based on optical, magnetic, fluorescent, separation, or delivery requirements.
Align the conjugation approach to the particle surface, antibody format, stability needs, and downstream assay or delivery behavior.
Support antibody–nanoparticle design around the final application rather than a generic particle-labeling workflow.
Match the particle platform to the required optical signal, magnetic handling, surface presentation, or delivery function.
Consider conjugate stability, antibody compatibility, and particle behavior under the intended experimental or analytical conditions.
Support project-specific nanoparticle conjugation needs where particle system, targeting design, signal requirements, or platform integration define the workflow.
Common applications for antibody nanoparticle conjugates include lateral flow assays, biosensors, magnetic separation, fluorescence imaging, targeted delivery, and diagnostic assay development.
Gold nanoparticle antibody conjugates are widely used for visible detection in rapid assay formats.
Nanoparticle conjugates can enhance sensitivity and surface recognition in biosensor platforms.
Quantum dots and related fluorescent nanoparticles support optical imaging and multiplex detection workflows.
Magnetic particle conjugates support capture, enrichment, purification, and target isolation workflows.
Antibody-functionalized particle systems can be used in targeting strategies for delivery-oriented applications, with performance influenced by particle chemistry and surface design.
Nanoparticle antibody conjugates are useful in assay development, platform engineering, and diagnostic system design.
Useful for fluorescence-based detection, microscopy, imaging, and assay development workflows.
Suitable for ELISA, immunodetection, and enzyme-amplified assay systems that require labeled antibodies.
Supports streptavidin-biotin assay formats, capture systems, and flexible downstream detection workflows.
See the broader antibody conjugation portfolio for enzyme, fluorescent, biotin, and other custom labeling approaches.
Tell us about your nanoparticle type, antibody format, and final application. We’ll help match the project to the right conjugation strategy.
For the fastest quote, include the nanoparticle type, antibody format, intended application, desired readout or functionality, and whether the project is focused on detection, separation, imaging, or targeted delivery.
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